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Título
Production of copper loaded lipid microparticles by PGSS® (particles from gas saturated solutions) process
Autor
Año del Documento
2018
Editorial
Elsevier B.V.
Documento Fuente
The Journal of Supercritical Fluids, 2018, vol.131, p. 124–129.
Résumé
Production of lipid particles loaded with metal nanoparticles by supercritical fluids based processes has been barely studied. In this work, copper nanoparticles were loaded into glyceryl palmitostearate microparticles by PGSS® (Particles from Gas Saturated Solutions). The effect of different variables, temperature (60-80 ºC), copper load (0.2-5%w/w) and water addition (0 – 40%w/w), in particle size and encapsulation efficiency has been studied. The dispersion of metal nanoparticles in the lipid has been determined by SEM-FIB coupled with EDS mapping. In all cases, mean particle size values lower than 70 μm have been obtained, and encapsulation efficiencies around 60% have been achieved. The addition of water has no negative effect in encapsulation efficiency nor in nanoparticles dispersion within the lipid microparticle, being important since nanoparticles are commonly synthetized in aqueous medium.
Palabras Clave
PGSS
Copper nanoparticles encapsulation
Lipid microparticles
Dispersion
Revisión por pares
SI
Patrocinador
Ministerio de Ciencia e Innovación and the University of Valladolid (JCI-2012-14992)
Fundação para a Ciência e a Tecnologia (FCT) (Grant PEst-OE/EQB/LA0004/2011: SFRH/BD/77350/2011)
Fundação para a Ciência e a Tecnologia (FCT) and FEDER 2014-2020 iNOVA4Health – UID/Multi/04462/2013 and UID/Multi/04551/2013 (GreenIT)
Fundação para a Ciência e a Tecnologia (FCT) (Grant PEst-OE/EQB/LA0004/2011: SFRH/BD/77350/2011)
Fundação para a Ciência e a Tecnologia (FCT) and FEDER 2014-2020 iNOVA4Health – UID/Multi/04462/2013 and UID/Multi/04551/2013 (GreenIT)
Version del Editor
Idioma
eng
Derechos
openAccess
Aparece en las colecciones
Fichier(s) constituant ce document
Tamaño:
1.348Mo
Formato:
Adobe PDF
Descripción:
Production of copper loaded lipid microparticles by PGSS® (particles from gas saturated solutions) process
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