Design of experiments in Chemistry

Abstract

The term design of experiments in analytical chemistry is associated to the establishment of adequate process conditions in order to: improve the instrumental conditions and/or extract the highest information from the experimental data. In this chapter there are practical problem solving strategies used to obtain a product or chemical process with desirable characteristics in an efficient mode. The information is presented as a tutorial and the main advantages and disadvantages are presented and discussed, emphasizing the effect of reduction of experimentation in the data quality.