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    Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/52368

    Título
    Effect of two meal replacement strategies on cardiovascular risk parameters in advanced age patients with obesity and osteoarthritis
    Autor
    López Gómez, Juan JoséAutoridad UVA
    Izaola Jauregui, OlatzAutoridad UVA
    Primo Martín, David
    Torres Torres, BeatrizAutoridad UVA
    Gómez Hoyos, EmiliaAutoridad UVA
    Ortolá Buigues, AnaAutoridad UVA
    Martín Ferrero, Miguel ÁngelAutoridad UVA Orcid
    Luis Román, Daniel Antonio deAutoridad UVA Orcid
    Año del Documento
    2020
    Editorial
    MDPI
    Descripción
    Producción Científica
    Documento Fuente
    Nutrients, 2020, vol. 12, n. 4, 976
    Abstract
    Background and aims: Meal replacement diets consist of replacing one or more meals with an artificial nutritional supplement. The objective of this study was to compare the effect of one against two meal replacement strategies on body composition and cardiovascular risk parameters in patients with obesity. Methods: A randomized clinical trial was designed with a modified hypocaloric diet with an artificial nutritional preparation replacing one or two meals for three months in patients with obesity and osteoarthritis pending orthopedic surgery. An anthropometric evaluation and a measurement of the body composition were done with bioelectrical impedance measurement at the beginning and at three months. Results: A total of 112 patients were recruited. Fifty-two patients (46.4%) were randomized to one replacement and 60 patients (53.6%) to two meal replacements. Eighty-one patients (72.3%) were women, and the average age was 61 (11.03) years. The percentage of weight loss at three months was 8.27 (4.79)% (one meal replacement: 7.98 (5.97)%; two meal replacements: 8.50 (3.48)%; p = 0.56). A decrease in fat mass measured by the fat mass index (FMI) was detected (one meal replacement: −2.15 (1.45) kg/m2 vs. two meal replacements: −2.78 (2.55) kg/m2; p > 0.05), and a relative increase in fat-free mass was observed (one meal replacement: +3.57 (4.61)% vs. two meal replacements: +2.14 (4.45)%; p > 0.05). A decrease in HOMA-IR, systolic blood pressure (SBP), and total cholesterol was observed in both groups without differences between them. Conclusions: The substitution strategies of one or two meal replacements were effective in weight loss and fat mass decrease without differences between the two groups. An improvement in lipid parameters, glycemic control, and systolic blood pressure was observed without differences between strategies.
    Palabras Clave
    Obesity
    Obesidad
    Osteoarthritis
    Osteoartritis
    Cardiovascular risk
    Riesgo cardiovascular
    ISSN
    2072-6643
    Revisión por pares
    SI
    DOI
    10.3390/nu12040976
    Version del Editor
    https://www.mdpi.com/2072-6643/12/4/976
    Propietario de los Derechos
    © 2020 The Authors
    Idioma
    eng
    URI
    https://uvadoc.uva.es/handle/10324/52368
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
    Aparece en las colecciones
    • DEP52 - Artículos de revista [181]
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