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Título
A population-based registry analysis on hospitalized COVID-19 patients with previous cardiovascular disease: Clinical profile, treatment, and predictors of death
Autor
Año del Documento
2021
Editorial
MDPI
Descripción
Producción Científica
Documento Fuente
Journal of Cardiovascular Development and Disease, 2021, Vol. 8, Nº. 12, 167
Resumo
A high percentage of patients with COVID-19 (coronavirus disease 2019) have previous cardiovascular disease (CVD). The findings presented here came from an epidemiological population-based registry study (real-world data) that enrolled all in-hospital COVID-19 patients with previous CVD from 1 March to 31 May 2020. Death, other comorbidities, hospital stay variables, ventilation type, and main clinical outcomes were evaluated. In Castile and Leon, 35.83% of the 7307 in-hospital COVID-19 patients who participated in this study had previous CVD, particularly arrhythmias (48.97%), cerebrovascular disease (25.02%), ischemic heart disease (22.8%), and chronic heart failure (20.82%). Of the patients, 21.36% were men and more than 90% were over 65 years of age, and the mortality rate achieved 32.93%. The most used medicines were antibiotics (91.41%), antimalarials (73.3%), steroids (46.64%), and antivirals (43.16%). The main predictors of death were age over 65 years (OR: 5), ventilation needs (OR: 2.81), treatment with anti-SIRS (systemic inflammatory response syndrome) medicines (OR: 1.97), antivirals (OR: 1.74) or steroids (OR: 1.68), SIRS (OR: 5.75), SARS (severe acute respiratory syndrome) (OR: 2.44), or AKI (acute kidney injury) (OR: 1.63) occurrence. Chronic heart failure and cerebrovascular disease were associated with a worse clinical course of COVID-19, especially in men older than 65 years with diabetes who developed SIRS, SARS, or AKI.
Materias (normalizadas)
COVID-19 (Disease)
COVID-19
Cardiovascular system - Diseases - Treatment
Cerebrovascular disease
Cardiology
Heart failure
Mortality
Materias Unesco
2420 Virología
3207.04 Patología Cardiovascular
ISSN
2308-3425
Revisión por pares
SI
Patrocinador
Gerencia Regional de Salud (Grant GRS COVID 10/A/20)
Version del Editor
Propietario de los Derechos
© 2021 The authors
Idioma
eng
Tipo de versión
info:eu-repo/semantics/publishedVersion
Derechos
openAccess
Aparece en las colecciones
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624.2Kb
Formato:
Adobe PDF
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