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Título
Relationship between the main components of the crystalline lens and the anterior chamber depth after cataract formation
Autor
Año del Documento
2023
Editorial
Springer
Descripción
Producción Científica
Documento Fuente
Graefe's Archive for Clinical and Experimental Ophthalmology, 2023.
Abstract
Purpose To assess the relationship between anterior chamber depth (ACD) and lens thickness (LT), as well as its three main
components (anterior and posterior cortex and nucleus thickness), in cataractous and non-cataractous eyes, depending on
the axial length (AxL).
Methods Anterior and posterior cortex and nucleus thickness of the crystalline lens, ACD, and AxL were measured using
optical low-coherence reflectometry in cataractous and non-cataractous eyes. They were also classified into hyperopia, emme-
tropia, myopia, and high myopia, depending on AxL; thus, eight subgroups were created. A minimum sample size of 44 eyes
(of 44 patients) for each group was recruited. Linear models were fitted for the whole sample and each AxL subgroup to assess
if there were differences in the relationships between the crystalline lens variables and ACD, including age as a covariate.
Results Three hundred seventy cataract patients (237 females, 133 males) and 250 non-cataract controls (180 females, 70
males), aged 70.5 ± 9.4 and 41.9 ± 15.5 years, respectively, were recruited. The mean AxL, ACD, and LT for the cataractous
and non-cataractous eyes were 23.90 ± 2.05, 24.11 ± 2.11, 2.64 ± 0.45, and 2.91 ± 0.49, 4.51 ± 0.38, 3.93 ± 0.44 mm, respec-
tively. The inverse relationship of LT, anterior and posterior cortex, and nucleus thickness with ACD was not significantly
(p ≥ 0.26) different between cataractous and non-cataractous eyes. Further subclassification of the sample depending on
AxL showed that the inverse relationship between the posterior cortex and ACD was no longer significant (p > 0.05) for any
non-cataractous AxL group. LT, anterior and posterior cortex, and nucleus thickness was not significantly (p ≥ 0.43) different
between cataractous and non-cataractous eyes for the whole sample, and all AxL groups after adjusting for age.
Conclusions The presence of cataracts does not modify the inverse relationship of the LT, anterior and posterior cortex, and
nucleus with ACD. And this relationship does not seem to depend importantly on AxL. Besides, the possible differences
in LT, anterior and posterior cortex, and nucleus between cataractous and non-cataractous eyes may not be caused by lens
opacification, but possibly by the progressive lens growth due to aging.
Materias Unesco
32 Ciencias Médicas
3201.09 Oftalmología
Palabras Clave
Lens thickness
Anterior cortex
Posterior cortex
Nucleus thickness
Axial length
Anterior chamber depth
Cataract
ISSN
0721-832X
Revisión por pares
SI
Patrocinador
Ministerio de Economía y Competitividad (Instituto de Salud Carlos III) through Research Projects (RETICS RD16/008/0001)
Publicación en abierto financiada por el Consorcio de Bibliotecas Universitarias de Castilla y León (BUCLE), con cargo al Programa Operativo 2014ES16RFOP009 FEDER 2014-2020 DE CASTILLA Y LEÓN, Actuación:20007-CL - Apoyo Consorcio BUCLE
Publicación en abierto financiada por el Consorcio de Bibliotecas Universitarias de Castilla y León (BUCLE), con cargo al Programa Operativo 2014ES16RFOP009 FEDER 2014-2020 DE CASTILLA Y LEÓN, Actuación:20007-CL - Apoyo Consorcio BUCLE
Version del Editor
Propietario de los Derechos
© 2023 The Author(s)
Idioma
eng
Tipo de versión
info:eu-repo/semantics/publishedVersion
Derechos
openAccess
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