Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/59913
Título
Antiviral activity of ribosome-inactivating proteins
Año del Documento
2021
Editorial
MDPI
Descripción
Producción Científica
Documento Fuente
Toxins, 2021, Vol. 13, Nº. 2, 80
Abstract
Ribosome-inactivating proteins (RIPs) are rRNA N-glycosylases from plants (EC 3.2.2.22) that inactivate ribosomes thus inhibiting protein synthesis. The antiviral properties of RIPs have been investigated for more than four decades. However, interest in these proteins is rising due to the emergence of infectious diseases caused by new viruses and the difficulty in treating viral infections. On the other hand, there is a growing need to control crop diseases without resorting to the use of phytosanitary products which are very harmful to the environment and in this respect, RIPs have been shown as a promising tool that can be used to obtain transgenic plants resistant to viruses. The way in which RIPs exert their antiviral effect continues to be the subject of intense research and several mechanisms of action have been proposed. The purpose of this review is to examine the research studies that deal with this matter, placing special emphasis on the most recent findings.
Materias (normalizadas)
Virus
Virology
Immunology
Plantas - Biotecnología
Plantas Transgénicas
Virus diseases
Proteins - Synthesis
Proteínas
Ribosomes - Structure
Virus - Tratamiento
Materias Unesco
2420 Virología
2412 Inmunología
2302 Bioquímica
Palabras Clave
Ribosome-inactivating protein
Proteínas inactivadoras de ribosomas
Virus-resistant transgenic plant
Plantas transgénicas resistentes a virus
rRNA glycosylase
ISSN
2072-6651
Revisión por pares
SI
Patrocinador
Junta de Castilla y León - (Grant VA033G19)
Version del Editor
Propietario de los Derechos
© 2021 The authors
Idioma
eng
Tipo de versión
info:eu-repo/semantics/publishedVersion
Derechos
openAccess
Aparece en las colecciones
Files in questo item
![Atribución 4.0 Internacional](/themes/Mirage2//images/creativecommons/cc-by.png)