Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/64386
Título
Fast determination of neonicotinoid insecticides in beeswax by ultra-high performance liquid chromatography-tandem mass spectrometry using an enhanced matrix removal-lipid sorbent for clean-up
Autor
Año del Documento
2018
Editorial
Elsevier
Descripción
Producción Científica
Documento Fuente
Microchemical Journal, Junio 2018, vol. 142. p. 70-77.
Résumé
This study is concerned with the development of a simple, rapid analytical method for simultaneously determining seven neonicotinoid insecticides (dinotefuran, nitenpyram, thiamethoxam, clothianidin, imidacloprid, acetamiprid and thiacloprid) in beeswax, by means of ultra-high performance liquid chromatography coupled to a quadrupole-time-of-flight mass detector. An efficient sample treatment is proposed (with average analyte recoveries between 93% and 106%) involving solvent extraction with a methanol and ethyl acetate mixture (70:30, v/v), centrifugation, freezing with dry ice, a dispersive solid phase extraction (enhanced matrix removallipid) followed by evaporation. Chromatographic analysis (10.5 min) was performed on a core-shell technologybased column (Kinetex® EVO C18). The method was fully validated in terms of selectivity, ruggedness, limits of detection (LODs) and quantification (LOQs), matrix effect, linearity, uncertainty, trueness and precision. Low LOQs, ranging from 1.2 to 4.9 μg/kg, were obtained in all cases. Finally, the proposed methods were applied to neonicotinoid analysis of twenty one beeswax samples from different Spanish regions, only one of the pesticides (imidacloprid) being detected at low levels (< LOQ).
Palabras Clave
Beeswax; Core-shell column; Dispersive solid-phase extraction; EMR-lipid sorbent; Neonicotinoid insecticides; UHPLC-MS/MS
ISSN
0026-265X
Revisión por pares
SI
Patrocinador
Este trabajo forma parte de los proyectos de investigación financiados por el Ministerio de Economía y Competitividad e INIA-FEDER (RTA2013-00042-C10-03 y 06).
Propietario de los Derechos
Elsevier
Idioma
eng
Tipo de versión
info:eu-repo/semantics/acceptedVersion
Derechos
openAccess
Aparece en las colecciones
Fichier(s) constituant ce document
Nombre:
Tamaño:
1.397Mo
Formato:
Adobe PDF
Descripción:
Artículo principal y material suplementario
![Attribution-NonCommercial-NoDerivatives 4.0 Internacional](/themes/Mirage2//images/creativecommons/cc-by-nc-nd.png)