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    Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/64580

    Título
    Modifications of serum levels of omentin-1 and other cardiovascular risk factors following weight loss secondary to a Mediterranean hypocaloric diet
    Autor
    Luis Román, Daniel Antonio deAutoridad UVA Orcid
    Izaola Jauregui, OlatzAutoridad UVA
    Primo Martín, David
    Aller de la Fuente, RocíoAutoridad UVA Orcid
    Año del Documento
    2018
    Documento Fuente
    Clin Nutr. 2018 Dec;37(6 Pt A):2280-2283
    Zusammenfassung
    Background & aims: Omentin-1 might play a role on insulin resistance, dyslipidemia and obesity. The aim of this investigation was to evaluate the influence of weight loss on omentin-1 concentrations after a hypocaloric diet with Mediterranean pattern. Methods: A Caucasian sample of 67 obese patients was analyzed before and after 3 months on a hypocaloric diet. Anthropometric parameters, blood pressure, fasting blood glucose, C-reactive protein (CRP), fasting insulin, insulin resistance (HOMA-IR), lipid concentrations and omentin-1 were measured. Results: Sixty-seven obese subjects were enrolled in the study. The mean age was 48.3 ± 8.0 years (range: 25e66) and the mean BMI 34.5 ± 4.8 kg/m2 (range: 30.2e40.8). Gender distribution was 50 females (74.6%) and 17 males (25.4%). After dietary intervention and in males and females; body mass index, weight, fat mass, waist circumference, blood pressure, glucose, LDL cholesterol, insulin and HOMA-IR decreased. Omentin-1 levels increase after dietary intervention (males vs females) (delta basal vs 3 months: 10.0 ± 3.8 ng/dl: p ¼ 0.01 vs 9.9 ± 4.1 ng/dl; p ¼ 0.03). In the multiple regression analysis adjusted for age and sex; BMI and insulin remained independently associated with baseline and posttreatment levels of omentin-1. Conclusions: Our investigation showed a significant increase in omentin-1 levels after weight loss secondary to a hypocaloric diet with a Mediterranean pattern.
    ISSN
    0261-5614
    Revisión por pares
    SI
    DOI
    10.1016/j.clnu.2017.11.009
    Idioma
    eng
    URI
    https://uvadoc.uva.es/handle/10324/64580
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
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    • DEP52 - Artículos de revista [181]
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    Nombre:
    clin nutriti. modificationts1-s2.0-S0261561417314073-main.pdf
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    252.6Kb
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    Universidad de Valladolid

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