Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/65047
Título
Palladium mono-N-protected amino acid complexes: experimental validation of the ligand cooperation model in C–H activation
Año del Documento
2023
Editorial
Royal Society of Chemistry
Descripción
Producción Científica
Documento Fuente
Chem. Sci., 2023, 14, 6688–6694
Resumo
Mechanistic proposals for the C–H activation reaction enabled by mono-N-protected amino acid ligands (MPAAs) have been supported by DFT calculations. The direct experimental observation of the ligand- assisted C–H activation has not yet been reported due to the lack of well-defined isolated palladium complexes with MPAAs that can serve as models. In this work, palladium complexes bearing chelating MPAAs (NBu4)[Pd(k2-N,O–AcN–CHR–COO)(C6F5)py] (Ac = MeC(O); R = H, Me) and [Pd(k2-N,O–MeNH– CH2–COO)(C6F5)py] have been isolated and characterized. Their evolution in a solution containing toluene leads to the C–H activation of the arene and the formation of the C6F5–C6H4Me coupling products. This process takes place only for the ligands with an acyl protecting group, showing the cooperating role of this group in a complex with a chelating MPAA, therefore experimentally validating this working model. The carboxylate group is inefficient in this C–H activation.
Materias (normalizadas)
Química
Materias Unesco
23 Química
Palabras Clave
Catálisis
Activación C-H
Cooperación metal-ligando
Paladio
ISSN
2041-6520
Revisión por pares
SI
Patrocinador
Ministerio de Ciencia e Innovación/AEI; Grant PID2019-111406GB-I00
Junta de Castilla y León-FEDER; Grant VA224P20
European Union / Ministerio de Ciencia e Innovación/Junta de Castilla y León; Grant C17.I01.P01.S21, H2MetAmo.
Junta de Castilla y León-FEDER; Grant VA224P20
European Union / Ministerio de Ciencia e Innovación/Junta de Castilla y León; Grant C17.I01.P01.S21, H2MetAmo.
Version del Editor
Idioma
spa
Tipo de versión
info:eu-repo/semantics/publishedVersion
Derechos
openAccess
Aparece en las colecciones
Arquivos deste item
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