Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/66463
Título
Gamma Power and Cognition in Patients with Schizophrenia and Their First-Degree Relatives
Año del Documento
2014
Documento Fuente
Neuropsychobiology 69(2):120-8
Résumé
Background: Gamma oscillations are essential for functional neural assembly formation underlying higher cerebral functions. Previous studies concerning gamma band power in schizophrenia have yielded diverse results.
Methods: In this study, we assessed gamma band power in minimally treated patients with schizophrenia, their first-degree relatives and healthy controls during an oddball paradigm performance, as well as the relation between gamma power and cognitive performance.
Results: We found a higher gamma power in the patient group than in the healthy controls at the P3, P4, Fz, Pz and T5 sites. Compared with their relatives, gamma power in the patients was only marginally higher over P3 and P4. We found a nearly significant inverse association between gamma power at F4 and Tower of London performance in the patients, as well as a significant inverse association between gamma power at T5 and verbal memory and working memory scores in the relatives.
Conclusion: These results support higher total gamma power in association with schizophrenia and its inverse association with cognitive performance in patients and their first-degree relatives.
ISSN
0302-282X
Revisión por pares
SI
Idioma
spa
Tipo de versión
info:eu-repo/semantics/draft
Derechos
openAccess
Aparece en las colecciones
Fichier(s) constituant ce document