Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/68993
Título
Protocolo de tratamiento del edema macular quístico asociado a retinosis pigmentaria y otras distrofias hereditarias de la retina
Autor
Año del Documento
2024-02
Editorial
Elsevier
Descripción
Producción Científica
Documento Fuente
Arch Soc Esp Oftalmol (Engl Ed). Feb 2024, vol. 99, n. 2, p. 67-81
Résumé
Inherited retinal dystrophies (IRD) are the leading cause of legal blindness in the wor-king population. Cystic macular edema (CME) is one of the treatable causes of visual loss,affecting up to 50% of the patients.A bibliographic review has been carried out combining “inherited retinal dystrophy”, “reti-nitis pigmentosa”, “macular edema” and a diagnostic-therapeutic protocol according to thelevels of evidence and recommendations of the “US Agency for Healthcare Research andQuality”.This protocol has been discussed in the monthly meetings of the XAREA DHR group withthe participation of more than 25 experts, creating a consensus document.The etiology of CME is multifactorial: dysfunction of the blood-retinal barrier, retinal pig-ment epithelium, and Müller cells, inflammation, and vitreous traction.OCT is the test of choice for the diagnosis and follow-up of CME associated with IRD.The drugs with the highest degree of scientific evidence are carbonic anhydrase inhibitors(IAC). Intravitreal corticosteroids, anti-VEGF, and vitrectomy with peeling of the internallimiting membrane do not have sufficient evidence.A treatment scheme is proposed for the CME in IRD in adults, another for pediatric patientsand an another for IRD and cataract surgery.Oral and topical IACs are effective in the treatment of CME secondary to IRD. Treatment withcorticosteroids, anti-VEGF, and vitrectomy are second-line options. Randomized clinicaltrials are required to establish the therapeutic scale in these patients.
Materias Unesco
3201.09 Oftalmología
Palabras Clave
Macular edema, Inherited retinal dystrophies, Retinitis pigmentosa, Cystoid macular edema, Carbonic anhydrase inhibitors, Steroids
ISSN
0365-6691
Revisión por pares
SI
Version del Editor
Propietario de los Derechos
Elsevier
Idioma
spa
Tipo de versión
info:eu-repo/semantics/publishedVersion
Derechos
openAccess
Aparece en las colecciones
- Retina - Artículos de Revista [14]
- Untitled [81]
- DEP11 - Artículos de revista [216]
Fichier(s) constituant ce document
![Attribution-NonCommercial-NoDerivatives 4.0 Internacional](/themes/Mirage2//images/creativecommons/cc-by-nc-nd.png)