A comparison of stem cell-related gene expression in the progenitor-rich limbal epithelium and the differentiating central corneal epithelium

Nieto Miguel, Teresa; Calonge, Margarita; De La Mata Sampedro, Ana; López-Paniagua, Marina; Galindo, Sara; de la Paz, María Fideliz; Corrales, Rosa María

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Título

A comparison of stem cell-related gene expression in the progenitor-rich limbal epithelium and the differentiating central corneal epithelium

Autor

Nieto Miguel, Teresa

Calonge, Margarita

De La Mata Sampedro, Ana

López-Paniagua, Marina

Galindo, Sara

de la Paz, María Fideliz

Corrales, Rosa María

Año del Documento

2011

Editorial

Molecular Vision

Descripción

Producción Científica

Documento Fuente

Molecular Vision, Agosto 2011, vol. 17, p. 2102-2117.

Résumé

Corneal epithelium is maintained by a population of stem cells (SCs) that have not been identified by specific molecular markers. The objective of this study was to find new putative markers for these SCs and to identify associated molecular pathways.

Materias (normalizadas)

Terapia Celular

Biología Celular

Oftalmologia

Materias Unesco

2407.05 Cultivo de Tejidos

2410.11 Organos Sensoriales

Palabras Clave

Limbo

Córnea

expresión genética

Revisión por pares

Patrocinador

This work was supported by Instituto de Salud Carlos III (CIBER-BBN CB06/01/003) and Junta de Castilla y León, Spain (Centro en Red de Medicina Regenerativa y Terapia Celular de Castilla y León; SAN673/VA/28/08). M. L-P. and S. G. were supported by fellowships from the Junta de Castilla y León.