RT info:eu-repo/semantics/article
T1 Role of sulfated protoglycans in early lens development
A1 Alonso Revuelta, María Isabel
A1 Gato Casado, Ángel Luis
A1 Moro Balbás, José Antonio
A1 Martín, Cristina
A1 Barbosa Cachorro, María Mercedes
A1 Callejo, Sagrario
A1 Barbosa Ayucar, Enrique
K1 Embriología
K1 Oftalmología - Investigación
AB The extracellular matrix has been sean to play a key role in many of the morphogenetic processes which take place during early ocular aniaga development. For soma time now it has been known that sulfatad proteoglycans are present ininitiallens development, as these molecules have been implied in morphogenetic processes such as lens invagination and induction (Webster et al., 1983, Peterson et al., 1995). The implication of sulfatad proteoglycans in these phenomena is attributed to their distribution pattern and their  coinciding with a particular process, or to the changas found in this distribution patternin certain mutant strains of aphakic mica (Zwaan and Webster, 1984). Nevertheless, there is no direct evidence to support the implication of proteoglycans in the formation processes of the lens vesicle and its subsequent development. In this paper,we offer the preliminary results of an experimental  study concerning selectiva disruption of sulfatad proteoglycans  synthesis by means of a P-D Xyloside, and its effect on lens growth.
PB Universidad de Valladolid. Facultad de Medicina
SN 1547-6278
YR 1995
FD 1995
LK http://uvadoc.uva.es/handle/10324/4965
UL http://uvadoc.uva.es/handle/10324/4965
LA eng
NO Organogénesis, p. 241-242
NO Producción Científica
DS UVaDOC
RD 28-abr-2024