RT info:eu-repo/semantics/article
T1 In vitro antifungal activity of chitosan-polyphenol conjugates against Phytophthora cinnamomi
A1 Matei, Petruta Mihaela
A1 Buzón Durán, Laura
A1 Pérez Lebeña, Eduardo
A1 Martín Gil, Jesús
A1 Iacomi, Beatrice Michaela
A1 Ramos Sánchez, María del Carmen
A1 Martín Ramos, Pablo
K1 Chitosan oligomers
K1 Oligómeros de quitosano
K1 Fungicides
K1 Fungicidas
K1 Phenolic compounds
K1 Compuestos fenólicos
K1 Silver nanoparticles
K1 Nanopartículas de plata
K1 32 Ciencias Médicas
AB Phytophthora cinnamomi is responsible for radical rot in a wide range of hosts, resulting in large economic and ecological losses worldwide. In Spain, it is responsible for diseases such as the oak decline or the chestnut blight. In this study, different polyphenol-stevioside inclusion compounds dispersed in a hydroalcoholic solution of chitosan oligomers have been investigated, with a view to their application as natural bioactive complexes to replace conventional systemic fungicides against this fungus. The polyphenols tested in vitro were curcumin, ferulic acid, gallic acid and silymarin. Three concentrations (125, 250 and 500 µg·mL−1) were assayed, with and without silver nanoparticles (AgNPs), and notable differences were found in the inhibition of mycelium growth, with EC50 and EC90 values ranging from 171 to 373.6 µg·mL−1, and from 446.2 to 963.7 µg·mL−1, respectively. The results obtained showed that the addition of AgNPs, despite their antimicrobial activity, did not always lead to synergies. In the case of P. cinnamomi, an unexpected antagonistic behavior was found for two of the polyphenols (curcumin and silymarin), while an additive behavior for ferulic acid and a synergistic behavior for gallic acid were attained. In view of their inhibitory power, the preparations based on ferulic acid with AgNPs and on silymarin without AgNPs are proposed for applications in crop and forests protection against P. cinnamomi.
PB MDPI
SN 2624-7402
YR 2020
FD 2020
LK https://uvadoc.uva.es/handle/10324/52596
UL https://uvadoc.uva.es/handle/10324/52596
LA eng
NO AgriEngineering, 2020, vol. 2, n. 1. p. 72-77
NO Producción Científica
DS UVaDOC
RD 03-jun-2024