RT info:eu-repo/semantics/article
T1 Influence of hyperglycemia associated with enteral nutrition on mortality in patients with stroke
A1 López Gómez, Juan José
A1 Delgado García, Esther
A1 Coto García, Cristina
A1 Torres Torres, Beatriz
A1 Gómez Hoyos, Emilia
A1 Serrano Valles, Cristina
A1 Castro Lozano, María Ángeles
A1 Arenillas Lara, Juan Francisco
A1 Luis Román, Daniel Antonio de
K1 Hyperglycaemia
K1 Hiperglucemia
K1 Enteral nutrition
K1 Nutrición enteral
K1 Dysphagia
K1 Disfagia
AB Objectives: To evaluate in patients admitted for stroke: (1) The frequency of hyperglycaemia associated with enteral nutrition (EN). (2) The risk of morbidity and mortality associated with the development of this type of hyperglycaemia. Methods: A longitudinal observational study was conducted in 115 non-diabetic patients admitted for stroke with EN. Age, functional capacity (Rankin scale), and blood plasma glucose (BPG) were recorded. Hyperglycaemia was considered as: a value higher than 126 mg/dL before the EN and/or a value higher than 150 mg/dL after a week of enteral nutrition. According to this, three groups were differentiated: HyperES: Those who had hyperglycemia before the beginning of the EN (33% patients); NoHyper: those who did not have hyperglycemia before or after (47.8% patients); and HyperEN: Those who did not have hyperglycemia before but suffered it after the beginning of the EN (19.1% patients). Results: The age was 72.72 (15.32) years. A higher rate of mortality was observed in the HyperEN group 45.50%, than HyperES 15.80% or NoHyper: 10.90%). A lower recovery of the oral feeding was observed in those patients of the HyperEN group 27.30%, than HyperES: 42.10% or NoHyper: 61.80%). In the multivariate analysis adjusting for age, sex, and Rankin scale the development of hyperglycemia in those who did not have it at the beginning (HyperEN) was an independent risk factor for non-recovery of the oral feeding (OR: 4.21 (1.20–14.79), p = 0.02); and mortality adjusted for age, sex and Rankin scale (OR: 6.83 (1.76–26.47), p < 0.01). Conclusions: In non-diabetic patients admitted for stroke with EN, the development of hyperglycaemia in relation to enteral nutrition supposes an independent risk factor for mortality and for the non-recovery of the oral feeding.
PB Elsevier
SN 2072-6643
YR 2019
FD 2019
LK https://uvadoc.uva.es/handle/10324/55988
UL https://uvadoc.uva.es/handle/10324/55988
LA eng
NO Nutrients, 2019, vol. 11, n. 5, 996
NO Producción Científica
DS UVaDOC
RD 18-may-2024