RT info:eu-repo/semantics/article
T1 Characterization of dysfunctional lens index and opacity grade in a healthy population
A1 Martínez Plaza, Elena
A1 Ruiz Fortes, Pedro
A1 Soto Negro, Roberto
A1 Hernández Rodríguez, Carlos J.
A1 Molina Martín, Ainhoa
A1 Arias Puente, Alfonso
A1 Piñero, David P.
K1 Eye - Diseases
K1 Ojo - Enfermedades y defectos
K1 Crystalline lens
K1 Cristalino - Enfermedades
K1 Cataract
K1 Cataratas (Oftalmología)
K1 Higher-order aberrations
K1 Ophthalmology
K1 Clinical biochemistry
K1 Bioquímica clínica
K1 Medical technology
K1 Dysfunctional lens syndrome
K1 Síndrome del cristalino disfuncional
K1 32 Ciencias Médicas
K1 3201.09 Oftalmología
K1 3314 Tecnología Médica
AB This study enrolled 61 volunteers (102 eyes) classified into subjects < 50 years (group 1) and subjects ≥ 50 years (group 2). Dysfunctional Lens Index (DLI); opacity grade; pupil diameter; and corneal, internal, and ocular higher order aberrations (HOAs) were measured with the i-Trace system (Tracey Technologies). Mean DLI was 8.89 ± 2.00 and 6.71 ± 2.97 in groups 1 and 2, respectively, being significantly higher in group 1 in all and right eyes (both p < 0.001). DLI correlated significantly with age (Rho = −0.41, p < 0.001) and pupil diameter (Rho = 0.20, p = 0.043) for all eyes, and numerous internal and ocular root-mean square HOAs for right, left, and all eyes (Rho ≤ −0.25, p ≤ 0.001). Mean opacity grade was 1.21 ± 0.63 and 1.48 ± 1.15 in groups 1 and 2, respectively, with no significant differences between groups (p ≥ 0.29). Opacity grade significantly correlated with pupil diameter for right and all eyes (Rho ≤ 0.33, p ≤ 0.013), and with some ocular root-mean square HOAs for right and all eyes (Rho ≥ 0.23, p ≤ 0.020). DLI correlates with age and might be used complementary to other diagnostic measurements for assessing the dysfunctional lens syndrome. Both DLI and opacity grade maintain a relationship with pupil diameter and internal and ocular HOAs, supporting that the algorithms used by the device may be based, in part, on these parameters.
PB MDPI
SN 2075-4418
YR 2022
FD 2022
LK https://uvadoc.uva.es/handle/10324/63184
UL https://uvadoc.uva.es/handle/10324/63184
LA eng
NO Diagnostics, 2022, Vol. 12, Nº. 5, 1167
NO Producción Científica
DS UVaDOC
RD 29-may-2024