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dc.contributor.authorCantera Ruiz de Pellón, Sara
dc.contributor.authorBordel Velasco, Sergio 
dc.contributor.authorLebrero Fernández, Raquel 
dc.contributor.authorGancedo Verdejo, Juan
dc.contributor.authorGarcía Encina, Pedro Antonio 
dc.contributor.authorMuñoz Torre, Raúl 
dc.date.accessioned2019-03-21T10:04:12Z
dc.date.available2019-03-21T10:04:12Z
dc.date.issued2019
dc.identifier.citationWorld Journal of Microbiology and Biotechnology, 2019, 35:16es
dc.identifier.issn0959-3993es
dc.identifier.urihttp://uvadoc.uva.es/handle/10324/35162
dc.descriptionProducción Científicaes
dc.description.abstractDespite the environmental relevance of CH4 and forthcoming stricter regulations, the development of cost-efficient and environmentally friendly technologies for CH4 abatement is still limited. To date, one of the most promising solutions for the mitigation of this important GHG consists of the bioconversion of CH4 into bioproducts with a high profit margin. In this context, methanotrophs have been already proven as cell-factories of some of the most expensive products synthesized by microorganisms. In the case of ectoine (1000 $ kg−1), already described methanotrophic genera such as Methylomicrobium can accumulate up to 20% (ectoine wt−1) using methane as the only carbon source. Moreover, α-methanotrophs, such as Methylosynus and Methylocystis, are able to store bioplastic concentrations up to 50–60% of their total cell content. More than that, methanotrophs are one of the greatest potential producers of methanol and exopolysaccharides. Although this methanotrophic factory could be enhanced throughout metabolic engineering, the valorization of CH4 into valuable metabolites has been already consistently demonstrated under continuous and discontinuous mode, producing more than one compound in the same bioprocess, and using both, single strains and specific consortia. This review states the state-of-the-art of this innovative biotechnological platform by assessing its potential and current limitations.es
dc.format.mimetypeapplication/pdfes
dc.language.isoenges
dc.publisherSpringeres
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject.classificationMetanoes
dc.subject.classificationMethanees
dc.subject.classificationTransformación biológicaes
dc.subject.classificationBio-transformationes
dc.titleBio-conversion of methane into high profit margin compounds: an innovative, environmentally friendly and cost-effective platform for methane abatementes
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.doihttps://doi.org/10.1007/s11274-018-2587-4es
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s11274-018-2587-4es
dc.peerreviewedNOes
dc.description.projectMinisterio de Economía, Industria y Competitividad- FEDER (Proyect (CTM2015-73228-JIN, H2020- MSCA-IF-2016: CH4BioVal-GA:750126 and Red NOVEDAR)es
dc.description.projectJunta de Castilla y León (programa de apoyo a proyectos de investigación – Ref. Project UIC71)es
dc.description.projectH2020- MSCA-IF-2016: CH4BioVal-GA:750126es
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/750126
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International


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