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dc.contributor.authorPérez Rubio, Alberto
dc.contributor.authorEiros Bouza, José María 
dc.date.accessioned2021-01-07T09:31:08Z
dc.date.available2021-01-07T09:31:08Z
dc.date.issued2018
dc.identifier.citationHuman Vaccines & Immunotherapeutics, 2018, vol. 14, n. 8, p. 1874-1882es
dc.identifier.issn2164-5515es
dc.identifier.urihttp://uvadoc.uva.es/handle/10324/44628
dc.descriptionProducción Científicaes
dc.description.abstractThe benefit of influenza vaccines is difficult to estimate due to the complexity of accurately assessing the burden of influenza. To improve the efficacy of influenza vaccines, vaccine manufacturers have developed quadrivalent influenza vaccine (QIV) formulations for seasonal vaccination by including both influenza B lineages. Three parallel approaches for producing influenza vaccines are attracting the interest of many vaccine manufacturing companies. The first and oldest is the conventional egg-derived influenza vaccine, which is used by the current licensed influenza vaccines. The second approach is a cell culture-derived influenza vaccine, and the third and most recent is synthetic vaccines. Here, we analyze the difficulties with vaccines production in eggs and compare this to cell culture-derived influenza vaccines and discuss the future of cell culture-derived QIVs.Keywords: Influenza vaccine, cell culture-derived, quadrivalent.es
dc.format.mimetypeapplication/pdfes
dc.language.isoenges
dc.publisherTaylor & Francises
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.classificationVacunaes
dc.subject.classificationInfluenzaes
dc.titleCell culture-derived flu vaccine: Present and futurees
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.holder© Taylor & Francises
dc.identifier.doi10.1080/21645515.2018.1460297es
dc.relation.publisherversionhttps://www.tandfonline.com/doi/full/10.1080/21645515.2018.1460297es
dc.identifier.publicationfirstpage1874es
dc.identifier.publicationissue8es
dc.identifier.publicationlastpage1882es
dc.identifier.publicationtitleHuman Vaccines & Immunotherapeuticses
dc.identifier.publicationvolume14es
dc.peerreviewedSIes
dc.identifier.essn2164-554Xes
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones
dc.subject.unesco32 Ciencias Médicases


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