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dc.contributor.authorGutiérrez Abejón, Eduardo
dc.contributor.authorHerrera Gómez, Francisco Magno
dc.contributor.authorCriado Espegel, Paloma
dc.contributor.authorÁlvarez González, Francisco Javier 
dc.date.accessioned2021-03-16T07:57:37Z
dc.date.available2021-03-16T07:57:37Z
dc.date.issued2020
dc.identifier.citationPharmaceuticals, 2020, vol. 13, n. 4. 14 p.es
dc.identifier.issn1424-8247es
dc.identifier.urihttp://uvadoc.uva.es/handle/10324/45756
dc.descriptionProducción Científicaes
dc.description.abstractAntidepressants are considered driving-impairing medicines (DIM). This is a population-based registry study that shows the trend in the use of antidepressants in Castile and León, Spain, from 2015 to 2018. Data on antidepressant dispensations at pharmacies and the adjusted use of these medicines by the driver population are presented. For the purposes of analysis, population distribution by age and gender has been taken into account, as well as the three Driving Under the Influence of Drugs, alcohol, and medicines (DRUID) categories. Antidepressants were used by 8.56% of the general population and 5.66% of drivers. Antidepressants were used more commonly by females than by males (12.12% vs. 4.87%, χ² = 1325.124, p = 0.001), and users increased as the age increased, even if women who drive used less antidepressants after turning 60 years of age. Chronic use of antidepressants was relevant (8.28%) in the same way as daily use (3.15%). Most of the consumption included SSRIs (4.99%), which are also known as “other antidepressants” (3.71%). Regardless of antidepressants consumed, users took 2.75 ± 1.19 DIMs, which are mainly anxiolytics (58.80%) and opioids (26.43%). Lastly, regarding consumption of antidepressants according to the DRUID classification, category I predominated over categories II and III. Our findings should serve as a starting point for health and traffic authorities to raise awareness of the risk for traffic accidents, especially involving SSRIs.es
dc.format.mimetypeapplication/pdfes
dc.language.isoenges
dc.publisherMDPIes
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.classificationAntidepressantses
dc.subject.classificationAntidepresivoses
dc.subject.classificationDrivinges
dc.subject.classificationConducciónes
dc.subject.classificationDrug utilizationes
dc.subject.classificationUso de medicamentoses
dc.subject.classificationTraffic accidentses
dc.subject.classificationAccidentes de tráficoes
dc.titleTrends in antidepressants use in Spain between 2015 and 2018: Analyses from a population-based registry study with reference to drivinges
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.holder© 2020 MDPIes
dc.identifier.doi10.3390/ph13040061es
dc.relation.publisherversionhttps://www.mdpi.com/1424-8247/13/4/61es
dc.peerreviewedSIes
dc.description.projectInstituto de Salud Carlos III (grant RD16/0017/0006)es
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones


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