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Título
Treatment of comorbid alcohol dependence and anxiety disorder: Review of the scientific evidence and recommendations for treatment
Autor
Año del Documento
2017
Editorial
Frontiers
Descripción
Producción Científica
Documento Fuente
Frontiers in Psychiatry, 2017, vol. 8. 14 p.
Zusammenfassung
Patients with alcohol-use disorders (AUDs) have a high prevalence of anxiety disorders (AnxDs). “Co-occurring disorders” refers to the coexistence of an AUD and/or drug related disorders with another non-addictive psychiatric disorder. The aim of this study was to assess the effectiveness of psychopharmacological treatments and psychotherapy in patients with AUD and AnxD and to propose recommendations for the treatment of patients with comorbid AnxDs and AUDs. Randomized clinical trials, meta-analyses, and clinical guidelines were retrieved from PubMed, Embase, and Cochrane databases. Paroxetine was found to be effective in social anxiety patients with alcohol dependence. Selective serotonin reuptake inhibitors (SSRIs), especially sertraline, showed effective results in posttraumatic stress disorder and in comorbid AnxD–AUD. However, SSRIs should be used with caution when patients are actively drinking because they may increase alcohol consumption. Buspirone, gabapentin, and pregabalin were found to be effective in comorbid AnxD–AUD. The treatment of dual AnxDs should start as early as possible. Since AUDs and AnxDs can reinforce each other, treatments targeting both pathologies can be effective. Women suffer from higher levels of stress and AnxDs than men, and they are also more vulnerable to maintaining alcohol consumption levels. Further research is needed in this comorbid patient population, including the study of different types of patients and gender perspectives.
Palabras Clave
Alcohol-use disorder
Trastorno por consumo de alcohol
Anxiety disorders
Trastorno de ansiedad
Comorbidity
Comorbilidad
Co-occurring disorders
Trastornos concurrentes
ISSN
1664-0640
Revisión por pares
SI
Patrocinador
Instituto de Salud Carlos III - Ministerio de Economía, Industria y Competitividad (grants RD12/0028/0012 and RD16/0017/0006)
Version del Editor
Propietario de los Derechos
© 2017 Frontiers
Idioma
eng
Tipo de versión
info:eu-repo/semantics/publishedVersion
Derechos
openAccess
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