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dc.contributor.authorLuis Román, Daniel Antonio de 
dc.contributor.authorGonzález Sagrado, Manuel
dc.contributor.authorConde, R.
dc.contributor.authorAller de la Fuente, Rocío 
dc.contributor.authorIzaola Jauregui, Olatz
dc.contributor.authorFuente, B. de la
dc.contributor.authorPérez Castrillon, José Luis 
dc.contributor.authorRomero, E.
dc.date.accessioned2014-09-09T11:30:19Z
dc.date.available2014-09-09T11:30:19Z
dc.date.issued2010
dc.identifier.citationDiabetes Research and Clinical Practice, 2010, vol. 89, p. 110-114es
dc.identifier.issn0168-8227es
dc.identifier.urihttp://uvadoc.uva.es/handle/10324/5882
dc.descriptionProducción Científicaes
dc.description.abstractBackground: The aim of the present study was to explore the relationship of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetic patients. Subjects: A population of 66 naı¨ve diabetic patients with obesity was analyzed. A complete nutritional and biochemical evaluation was performed. Results: The mean age 56.9 11.6 years and the mean BMI was 37.8 6.3. Patients were divided in two groups by median resistin value (3.3 ng/ml), group I (patients with the low values, average value 2.5 0.5) and group II (patients with the high values, average value 4.8 1.8). Patients in the group I had lower waist circumference, total cholesterol, LDLcholesterol and C-reactive protein than patients in group II. Correlation analysis showed a significant correlation among resistin levels and the independent variables; BMI (r = 0.26; p < 0.05), waist circumference (r = 0.38; p < 0.05), fat mass (r = 0.28; p < 0.05), LDL-cholesterol (r = 0.3; p < 0.05), C-reactive protein (r = 0.28; p < 0.05). In the multivariate analysis, resistin concentration increase 0.024 ng/ml (CI 95%: 0.006–0.42) for each mg/dl of C-reactive protein. Conclusion: Circulating resistins are associated with C-reactive protein in an independent way in naı¨ve diabetic patients.es
dc.format.mimetypeapplication/pdfes
dc.language.isoenges
dc.publisherElsevieres
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectCardiovascular, Aparato - Enfermedadeses
dc.subjectDiabetes
dc.titleRelation of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetes obese patientses
dc.typeinfo:eu-repo/semantics/articlees
dc.identifier.doi10.1016/j.diabres.2010.03.031es
dc.identifier.publicationfirstpage110es
dc.identifier.publicationlastpage114es
dc.identifier.publicationtitleDiabetes Research and Clinical Practicees
dc.identifier.publicationvolume89es
dc.peerreviewedSIes
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International


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