dc.contributor.author | Luis Román, Daniel Antonio de | |
dc.contributor.author | González Sagrado, Manuel | |
dc.contributor.author | Conde, R. | |
dc.contributor.author | Aller de la Fuente, Rocío | |
dc.contributor.author | Izaola Jauregui, Olatz | |
dc.contributor.author | Fuente, Beatriz de la | |
dc.contributor.author | Pérez Castrillon, José Luis | |
dc.contributor.author | Romero, E. | |
dc.date.accessioned | 2014-09-09T11:30:19Z | |
dc.date.available | 2014-09-09T11:30:19Z | |
dc.date.issued | 2010 | |
dc.identifier.citation | Diabetes Research and Clinical Practice, 2010, vol. 89, p. 110-114 | es |
dc.identifier.issn | 0168-8227 | es |
dc.identifier.uri | http://uvadoc.uva.es/handle/10324/5882 | |
dc.description | Producción Científica | es |
dc.description.abstract | Background: The aim of the present study was to explore the relationship of resistin levels
with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetic
patients.
Subjects: A population of 66 naı¨ve diabetic patients with obesity was analyzed. A complete
nutritional and biochemical evaluation was performed.
Results: The mean age 56.9 11.6 years and the mean BMI was 37.8 6.3. Patients were
divided in two groups by median resistin value (3.3 ng/ml), group I (patients with the low
values, average value 2.5 0.5) and group II (patients with the high values, average value
4.8 1.8). Patients in the group I had lower waist circumference, total cholesterol, LDLcholesterol
and C-reactive protein than patients in group II. Correlation analysis showed a
significant correlation among resistin levels and the independent variables; BMI (r = 0.26;
p < 0.05), waist circumference (r = 0.38; p < 0.05), fat mass (r = 0.28; p < 0.05), LDL-cholesterol
(r = 0.3; p < 0.05), C-reactive protein (r = 0.28; p < 0.05). In the multivariate analysis, resistin
concentration increase 0.024 ng/ml (CI 95%: 0.006–0.42) for each mg/dl of C-reactive protein.
Conclusion: Circulating resistins are associated with C-reactive protein in an independent
way in naı¨ve diabetic patients. | es |
dc.format.mimetype | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | Elsevier | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject | Cardiovascular, Aparato - Enfermedades | es |
dc.subject | Diabetes | |
dc.title | Relation of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetes obese patients | es |
dc.type | info:eu-repo/semantics/article | es |
dc.identifier.doi | 10.1016/j.diabres.2010.03.031 | es |
dc.identifier.publicationfirstpage | 110 | es |
dc.identifier.publicationlastpage | 114 | es |
dc.identifier.publicationtitle | Diabetes Research and Clinical Practice | es |
dc.identifier.publicationvolume | 89 | es |
dc.peerreviewed | SI | es |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | |