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    Por favor, use este identificador para citar o enlazar este ítem:http://uvadoc.uva.es/handle/10324/5882

    Título
    Relation of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetes obese patients
    Autor
    Luis Román, Daniel Antonio deAutoridad UVA Orcid
    González Sagrado, Manuel
    Conde, R.
    Aller de la Fuente, RocíoAutoridad UVA
    Izaola Jauregui, Olatz
    Fuente, Beatriz de la
    Pérez Castrillon, José LuisAutoridad UVA
    Romero, E.
    Año del Documento
    2010
    Editorial
    Elsevier
    Descripción
    Producción Científica
    Documento Fuente
    Diabetes Research and Clinical Practice, 2010, vol. 89, p. 110-114
    Abstract
    Background: The aim of the present study was to explore the relationship of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetic patients. Subjects: A population of 66 naı¨ve diabetic patients with obesity was analyzed. A complete nutritional and biochemical evaluation was performed. Results: The mean age 56.9 11.6 years and the mean BMI was 37.8 6.3. Patients were divided in two groups by median resistin value (3.3 ng/ml), group I (patients with the low values, average value 2.5 0.5) and group II (patients with the high values, average value 4.8 1.8). Patients in the group I had lower waist circumference, total cholesterol, LDLcholesterol and C-reactive protein than patients in group II. Correlation analysis showed a significant correlation among resistin levels and the independent variables; BMI (r = 0.26; p < 0.05), waist circumference (r = 0.38; p < 0.05), fat mass (r = 0.28; p < 0.05), LDL-cholesterol (r = 0.3; p < 0.05), C-reactive protein (r = 0.28; p < 0.05). In the multivariate analysis, resistin concentration increase 0.024 ng/ml (CI 95%: 0.006–0.42) for each mg/dl of C-reactive protein. Conclusion: Circulating resistins are associated with C-reactive protein in an independent way in naı¨ve diabetic patients.
    Materias (normalizadas)
    Cardiovascular, Aparato - Enfermedades
    Diabetes
    ISSN
    0168-8227
    Revisión por pares
    SI
    DOI
    10.1016/j.diabres.2010.03.031
    Idioma
    eng
    URI
    http://uvadoc.uva.es/handle/10324/5882
    Derechos
    openAccess
    Collections
    • DEP52 - Artículos de revista [55]
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