Skip navigation
Please use this identifier to cite or link to this item:
Title: Relation of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetes obese patients
Authors: Luis Román, Daniel Antonio de
González Sagrado, Manuel
Conde, R.
Aller, R.
Izaola, O.
Fuente, B. de la
Pérez Castrillón, José Luis
Romero, E.
Issue Date: 2010
Publisher: Elsevier
Description: Producción Científica
Citation: Diabetes Research and Clinical Practice, 2010, vol. 89, p. 110-114
Abstract: Background: The aim of the present study was to explore the relationship of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetic patients. Subjects: A population of 66 naı¨ve diabetic patients with obesity was analyzed. A complete nutritional and biochemical evaluation was performed. Results: The mean age 56.9 11.6 years and the mean BMI was 37.8 6.3. Patients were divided in two groups by median resistin value (3.3 ng/ml), group I (patients with the low values, average value 2.5 0.5) and group II (patients with the high values, average value 4.8 1.8). Patients in the group I had lower waist circumference, total cholesterol, LDLcholesterol and C-reactive protein than patients in group II. Correlation analysis showed a significant correlation among resistin levels and the independent variables; BMI (r = 0.26; p < 0.05), waist circumference (r = 0.38; p < 0.05), fat mass (r = 0.28; p < 0.05), LDL-cholesterol (r = 0.3; p < 0.05), C-reactive protein (r = 0.28; p < 0.05). In the multivariate analysis, resistin concentration increase 0.024 ng/ml (CI 95%: 0.006–0.42) for each mg/dl of C-reactive protein. Conclusion: Circulating resistins are associated with C-reactive protein in an independent way in naı¨ve diabetic patients.
Keywords: Cardiovascular, Aparato - Enfermedades
ISSN: 0168-8227
Peer Review: SI
DOI: 10.1016/j.diabres.2010.03.031
Language: eng
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:DEP52 - Artículos de revista

Files in This Item:
File Description SizeFormat 
CASTRILLON 21[1].pdfPD-93356,75 kBAdobe PDFThumbnail

This item is licensed under a Creative Commons License Creative Commons

University of Valladolid
Powered by MIT's. DSpace software, Version 5.5