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Por favor, use este identificador para citar o enlazar este ítem: http://uvadoc.uva.es/handle/10324/5882
Título: Relation of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetes obese patients
Autor: Luis Román, Daniel Antonio de
González Sagrado, Manuel
Conde, R.
Aller, R.
Izaola, O.
Fuente, B. de la
Pérez Castrillón, José Luis
Romero, E.
Año del Documento: 2010
Editorial: Elsevier
Descripción: Producción Científica
Documento Fuente: Diabetes Research and Clinical Practice, 2010, vol. 89, p. 110-114
Resumen: Background: The aim of the present study was to explore the relationship of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetic patients. Subjects: A population of 66 naı¨ve diabetic patients with obesity was analyzed. A complete nutritional and biochemical evaluation was performed. Results: The mean age 56.9 11.6 years and the mean BMI was 37.8 6.3. Patients were divided in two groups by median resistin value (3.3 ng/ml), group I (patients with the low values, average value 2.5 0.5) and group II (patients with the high values, average value 4.8 1.8). Patients in the group I had lower waist circumference, total cholesterol, LDLcholesterol and C-reactive protein than patients in group II. Correlation analysis showed a significant correlation among resistin levels and the independent variables; BMI (r = 0.26; p < 0.05), waist circumference (r = 0.38; p < 0.05), fat mass (r = 0.28; p < 0.05), LDL-cholesterol (r = 0.3; p < 0.05), C-reactive protein (r = 0.28; p < 0.05). In the multivariate analysis, resistin concentration increase 0.024 ng/ml (CI 95%: 0.006–0.42) for each mg/dl of C-reactive protein. Conclusion: Circulating resistins are associated with C-reactive protein in an independent way in naı¨ve diabetic patients.
Materias (normalizadas): Cardiovascular, Aparato - Enfermedades
Diabetes
ISSN: 0168-8227
Revisión por Pares: SI
DOI: 10.1016/j.diabres.2010.03.031
Idioma: eng
URI: http://uvadoc.uva.es/handle/10324/5882
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:DEP52 - Artículos de revista

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