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Título
Association between vitamin D deficiency and heart failure in the elderly
Autor
Año del Documento
2011
Editorial
Elsevier Ireland Ltd.
Descripción
Producción Científica
Documento Fuente
International Journal of Cardiology, 2011, p. 407-408
Résumé
Vitamin D (25-OH-vitamin D) is a hormone which acts on the
calcium-phosphorus metabolism and also has extraskeletal effects.
In the cardiovascular system, it regulates the renin-angiotensinaldosterone
system (RAAS), inhibits vascular smooth muscle proliferation,
and suppresses cardiac hypertrophy and hypercontractility [1].
We assessed the relationship between vitamin D deficiency
and heart failure (HF) in an elderly population. We carried out a
prospective case-control study in the Internal Medicine Department,
Rio Hortega Hospital, Valladolid in 2010. Twenty-five patients were
diagnosed with HF and 19 were institutionalized controls with no
history of cardiovascular disease (CVD). The age of patients and control
group was similar (83±7 years vs. 85±8 years, pN0.05). The sex
distribution don't show differences. HF was diagnosed according to
clinical and laboratory criteria (B-type natriuretic peptideN400 pg/mL).
Vitamin D insufficiency was defined as levelsb20 ng/ml and deficiency
asb10 ng/ml. Two-dimensional echocardiography evaluated systolic
and diastolic function, pulmonary artery systolic pressure (PASP), atrial
fibrillation and valvular disease in the HF group.
Materias (normalizadas)
Osteoporosis
ISSN
0167-5273
Revisión por pares
SI
Idioma
eng
Derechos
openAccess
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