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dc.contributor.authorCastro Alija, María José 
dc.contributor.authorJiménez Pérez, José María 
dc.contributor.authorLópez Vallecillo, María 
dc.contributor.authorCao Torija, María José 
dc.contributor.authorSantos Torres, Jair
dc.contributor.authorLópez, Alberto
dc.contributor.authorMoreno, Ana
dc.contributor.authorRuiz-Tovar Polo, Jaime
dc.date.accessioned2023-06-26T11:28:06Z
dc.date.available2023-06-26T11:28:06Z
dc.date.issued2021
dc.identifier.citationNutrients, 2021, Vol. 13, Nª. 2, 711es
dc.identifier.issn2072-6643es
dc.identifier.urihttps://uvadoc.uva.es/handle/10324/59956
dc.descriptionProducción Científicaes
dc.description.abstractBackground: The outcome of colorectal cancer is mostly based on TNM classification. There are several factors determining that patients with the same tumoral stage present different outcomes. The nutritional status has been related to the immunological response and may affect the oncologic results. The purpose of this study was to determine if preoperative nutritional parameters may predict the oncologic outcome in patients with early colorectal cancer. Methods: A prospective observational study of patients undergoing elective surgery for colorectal cancer was performed with stage I. Preoperative nutritional assessment included glycemic and lipid profiles, total proteins, and albumin levels. These parameters were correlated with tumoral recurrence during a follow-up of at least 24 months. Results: During the period of study, 744 patients were operated on and 228 (30.6%) followed the inclusion criteria for this study. Recurrence rate was 5.7% (13 patients). Patients with hypoproteinemia showed a 7.8-fold greater risk of recurrence during the first 24 months after surgery [OR 7.8 (CI95% 1.3–48), p = 0.012]. Patients with glycated hemoglobin levels (HbA1c) > 6.2% showed a 2.3 increased risk of recurrence [OR 2.3 (CI95% 1.1–4.7; p = 0.01]. Conclusions: Preoperative values of total proteins and HbA1c correlate with the recurrence rate in early colorectal cancer.es
dc.format.mimetypeapplication/pdfes
dc.language.isoenges
dc.publisherMDPIes
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectSurgical oncologyes
dc.subjectCancer Researches
dc.subjectOncologyes
dc.subjectColorectal Surgeryes
dc.subjectRectum - Surgeryes
dc.subjectCàncer colorectales
dc.subjectRecto - Cánceres
dc.subjectColon - Cánceres
dc.subjectOutcome assessment (Medical care)es
dc.subjectProteinses
dc.subjectProteínases
dc.subjectGlycosylated hemoglobin - Measurementes
dc.subjectNutritiones
dc.titleImpact of preoperative total proteins and glycated hemoglobin on recurrences after early colorectal canceres
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.holder© 2021 The authorses
dc.identifier.doi10.3390/nu13020711es
dc.relation.publisherversionhttps://www.mdpi.com/2072-6643/13/2/711es
dc.identifier.publicationfirstpage711es
dc.identifier.publicationissue2es
dc.identifier.publicationtitleNutrientses
dc.identifier.publicationvolume13es
dc.peerreviewedSIes
dc.identifier.essn2072-6643es
dc.rightsAtribución 4.0 Internacional*
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones
dc.subject.unesco32 Ciencias Médicases
dc.subject.unesco3201.01 Oncologíaes


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