dc.contributor.author | Fernández Peña, Laura | |
dc.contributor.author | González-Andrés, Paula | |
dc.contributor.author | Barbero, Asunción | |
dc.date.accessioned | 2025-07-04T17:00:32Z | |
dc.date.available | 2025-07-04T17:00:32Z | |
dc.date.issued | 2024 | |
dc.identifier.citation | RSC Adv., 2024, 14, 707–711 | es |
dc.identifier.uri | https://uvadoc.uva.es/handle/10324/76255 | |
dc.description.abstract | We herein present a selective methodology for the synthesis of disubstituted dihydropyrans by silyl-Prins cyclization of Z-vinylsilyl alcohols mediated by trimethylsilyl trifluoromethanesulfonate (TMSOTf). The reaction features broad substrate scope, short reaction times and ease of process scale-up. Moreover, to showcase the applicability of the proposed method, we also report a facile and linear synthesis of analogues of rhopaloic acid and natural doremox fragrance. | es |
dc.format.mimetype | application/pdf | es |
dc.language.iso | eng | es |
dc.publisher | RSC | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.title | Towards an efficient methodology for the synthesis of functionalized dihydropyrans by silyl-Prins cyclization: access to truncated natural products | es |
dc.type | info:eu-repo/semantics/article | es |
dc.identifier.doi | https://doi.org/10.1039/d3ra07520f | es |
dc.identifier.publicationfirstpage | 707 | es |
dc.identifier.publicationlastpage | 711 | es |
dc.identifier.publicationtitle | Towards an efficient methodology for the synthesis of functionalized dihydropyrans by silyl-Prins | es |
dc.identifier.publicationvolume | 14 | es |
dc.peerreviewed | SI | es |
dc.type.hasVersion | info:eu-repo/semantics/draft | es |