Skip navigation
Por favor, use este identificador para citar o enlazar este ítem: http://uvadoc.uva.es/handle/10324/21847
Título: Formation of calcium phosphate nanostructures under the influence of self-assembling hybrid elastin-like-statherin recombinamers
Autor: Hamed Misbah, Mohamed
Espanol, M.
Quintanilla Sierra, Luis
Ginebra, M. P.
Rodríguez Cabello, José Carlos
Año del Documento: 2016
Editorial: Royal Society of Chemistry
Descripción: Producción Científica
Documento Fuente: RSC Advances, 2016, 6, p. 31225-31234
Resumen: The self-assembling properties of thermally-sensitive amphiphilic elastin-like multiblock recombinamers have been combined with the capacities of calcium phosphate binding of the SNA15 epitope inspired by the salivary protein statherin. In this regard, the interaction between calcium and phosphate ions was examined in the presence of two hybrid recombinamers. The first recombinamer comprised a simple amphiphilic diblock in which the SNA15 epitopes were combined, at the gene level, to the hydrophilic end. This recombinamer can self-assemble into nanoparticles that can control the transformation of amorphous calcium phosphate (ACP) into a fibre-like hydroxyapatite structure. In the other recombinamer, the SNA15 domains are distributed along the monomer chain, with the hydrophilic blocks being distributed amongst the hydrophobic ones. In this case, the resulting nanohybrid ACP/ recombinamer organises into neuron-like structures. Thus, combining the amphiphilic elastin-like recombinamers to the SNA15 functionality is a powerful mean to tune the formation of different complex calcium phosphate nanostructures
Materias (normalizadas): Calcio
Fosfátos
ISSN: ISSN: 2046-2069
Revisión por Pares: SI
DOI: 10.1039/C6RA01100D
Patrocinador: info:eu-repo/grantAgreement/EC/FP7/263363
info:eu-repo/grantAgreement/EC/FP7/278557
Patrocinador: Junta de Castilla y León (programa de apoyo a proyectos de investigación – Ref. VA244U13)
Version del Editor: www.rsc.org/advances
Idioma: spa
URI: http://uvadoc.uva.es/handle/10324/21847
Derechos: info:eu-repo/semantics/embargoedAccess
Aparece en las colecciones:Documentos OpenAire(Open Access Infrastructure for Research in Europe)
DEP60 - Artículos de revista

Ficheros en este ítem:
Fichero Descripción TamañoFormato 
Formation-calcium-phosphateof self-assembling.pdf683,31 kBAdobe PDFThumbnail
Visualizar/Abrir


Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons Creative Commons

Comentarios
Universidad de Valladolid
Powered by MIT's. DSpace software, Version 5.5