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Title: Decreased levels of GABA in the inferior colliculus of the epilepsy-prone hamster (GPG/Vall)
Authors: Fuentes Santamaría, Verónica
Alvarado, Juan Carlos
Herranz, Antonio S.
García Atarés, Natividad
López, Dolores E.
Issue Date: 2008
Publisher: Elsevier
Description: Producción Científica
Citation: Epilepsy Research, vol.79. p. 224-227
Abstract: Abnormalities in GABA levels in the central nucleus of the inferior colliculus (CNIC) of the epilepsy-prone hamster (GPG/Vall) were evaluated by using immunohistochemistry, densitometry and high performance liquid chromatography (HPLC). These findings demonstrate a decrease both in GABA immunostaining (neuropil and neurons) and in GABA concentration (HPLC) in the CNIC of the epileptic hamster compared to control animals. These decreases may reflect a reduced availability of this neurotransmitter that may act as an audiogenic seizure-initiating factor.
Keywords: Densitometría
Classification: Amino Ácido
Peer Review: SI
DOI: 10.1016/j.eplepsyres.2008.02.003
Language: eng
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:DEP04 - Artículos de revista

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