|Title: ||Reflux patterns and risk factors of primary varicose veins clinical severity|
|Authors: ||García Gimeno, M.|
Rodríguez Camarero, S.
Tagarro Villalba, S.
Ramalle Gomara, Enrique
Ajona García, J. A.
González Arranz, Miguel Ángel
López García, D.
González González, E.
Vaquero Puerta, Carlos
|Issue Date: ||2012|
|Publisher: ||Universidad de Valladolid. Facultad de Medicina|
|Description: ||Producción Científica|
|Citation: ||Phlebology, 2012, 1-9|
Objectives: Primarily, to determine the association between the clinical severity of primary
varicose veins and different reflux patterns in an anatomic and haemodynamic clinical
study using duplex ultrasonography (DU). Secondly, to analyse the association of clinical
severity with other aspects, such as risk factors for chronic venous insufficiency (CVI) and
other concurrent diseases.
Method: A total of 2036 limbs were evaluated using DU. Clinical status was characterized by
the CEAP (clinical, aetiological, anatomical and pathological elements) classification. The
degree of clinical severity was grouped into two categories, mild to moderate CVI (C1–C3)
and severe CVI, characterized by the presence of skin changes (C4–C6). We analysed the
association of the different reflux patterns with CEAP status.
Results: Saphenofemoral junction (SFJ) reflux of the great saphenous vein (GSV) was
associated with the most severe form of the disease (odds ratio [OR] ¼ 2.96; confidence
interval [CI] 95%: 2.2–3.8), whereas competent SFJ of the GSV with reflux from proximal
veins (OR ¼ 2; CI 95%: 1.4–2.7) and the pure non-saphenous reflux (OR ¼ 4.1; CI 95%:
1.8–9.0) were associated with mild to moderate CVI. Obesity increased the frequency of
severe CVI 2.7 times (OR ¼ 2.7; CI 95%: 1.6–4.6); being a woman also increased the
frequency of more severe disease 1.3 times (OR ¼ 1.3; CI 95%: 1.0–1.7).
Conclusion: Anatomical and haemodynamic studies by DU are postulated as a useful
diagnostic tool that allow, by identifying the pattern of venous reflux of varicose
pathology, characterization of the probable association to CVI clinical severity.|
|Peer Review: ||SI|
|Appears in Collections:||DEP11 - Artículos de revista|