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Title: Involvement of sulfated proteoglycans in embryonic brain expansion at earliest stages of development in rat embryos
Authors: Alonso Revuelta, María Isabel
Gato Casado, Ángel Luis
Moro Balbás, José Antonio
Martina, P.
Barbosa, Enrique
Issue Date: 1999
Publisher: Karger
Description: Producción Científica
Citation: Cell Tissues Organs, 1999, vol. 165, p.1-9
Abstract: The expansive force generated by the positive pressure of the neural tube fluid confined inside the brain vesicles has been shown to be a key factor during the earliest stages of brain morphogP.nesis and development of chick embryos. In a previous study,we demonstrated the existence of an intracavity extracellular matrix rich in condroitin sulfate in this species, which could be in­ volved in the regulation of the expa nsive process. In this report, scanning electron microscopy and immunohisto­ chemistry show that,after neurulation,a similar extracel­ lular matrix rich in chondroitin sulfate is present inside the brain vesicles of rat embryos during early enlarge­ ment of the brain anlage. In vitro treatment of rat embryos- Abbreviations used in this paper bryos with B-0-xyloside (a chemical compound which
Keywords: Embriología
Cerebro - Enfermedades
Peer Review: SI
Language: eng
Rights: info:eu-repo/semantics/openAccess
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Appears in Collections:DEP04 - Artículos de revista

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