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Por favor, use este identificador para citar o enlazar este ítem: http://uvadoc.uva.es/handle/10324/8219
Título: Can we measure mesopic pupil size with the cobalt blue light slit-lamp biomicroscopy method?
Autor: Maldonado López, Miguel José
López Miguel, Alberto
Piñero, David P.
Juberías, José R.
Nieto, Juan C.
Alió, Jorge L.
Año del Documento: 2012
Editorial: Springer Verlag
Descripción: Producción Científica
Documento Fuente: Graefes Arch Clin Exp Ophthalmol. 2012 Nov;250(11):1637-47
Resumen: The aim of this work is to assess a previously described slit-lamp biomicroscopy-based method (SLBM) for measuring pupil diameter and compare it to Colvard infrared pupillometry (CIP). METHODS: Two examiners performed three repeated measurements with each instrument in 40 healthy eyes. We determined the agreement of SLBM and CIP, intraobserver and interobserver repeatabilities, and interobserver concordance (kappa) and SLBM ability for detecting pupil sizes over 6.0 mm. RESULTS: The mean (±standard deviation [SD]) pupil diameter was 5.81 ± 0.70 mm with SLBM and 6.26 ± 0.68 mm with CIP (p = 0.01) averaging both examiner's results. Mean differences between the SLBM and CIP were -0.60 mm and -0.30 mm for each examiner using the average of the three readings (p = 0.02), and they were very similar using the first reading. Intraobserver reproducibility: the width of the 95% LoA ranged from 1.79 to 2.30 mm. The ICCs were 0.97 and 0.92 for SLBM, and 0.96 and 0.90 for CIP. Interobserver reproducibility: the width of the LoA ranged from 1.82 to 2.09 mm. Kappa statistics were 0.39 and 0.49 for the first and mean SLBM readings, respectively, and 0.45 for both the first and mean CIP readings. Sensitivity and specificity of SLBM for detection of pupils larger than 6 mm ranged from 55.56% to 73.68% and from 76.19% to 95.45%, respectively. The best trade-off between sensitivity and specificity ranged from 5.4 mm to 6.2 mm. CONCLUSIONS: Although the SLBM is quite repeatable, it underestimates mesopic pupil size and shows a too wide range of agreement with CIP. SLBM shows low sensitivity in detecting pupils larger than 6 mm, which may be misleading when planning anterior segment surgery. Previous grading-consensus training strategies may increase interrater reproducibility, and compensation for the systematic underestimation could improve accuracy of the SLBM.
Materias (normalizadas): Cirugía oftalmológica
ISSN: 0721-832X
Revisión por Pares: SI
DOI: 10.1007/s00417-011-1909-0
Idioma: eng
URI: http://uvadoc.uva.es/handle/10324/8219
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:DEP11 - Artículos de revista

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