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Title: Prevalence of ocular and oculodermal melanocytosis in Spanish population with uveal melanoma
Authors: Carreño, E.
Saornil Álvarez, María Antonia
García-Álvarez, C.
López Lara, Francisco
Frutos Baraja, J. M. de
Almaraz Gómez, Ana
Issue Date: 2012
Publisher: Nature Publishing Group
Description: Producción Científica
Citation: Eye . 2012 Jan;26(1):159-156
Abstract: The aim of this study was to determine the prevalence of ocular and oculodermal melanocytosis (ODM) among patients with uveal melanoma (UM) in a Spanish population. METHODS: Retrospective review of the medical records of patients with ODM among patients with UM. RESULTS: Ten (11 eyes) of 400 patients (2.7%) with UM associated had ODM. The mean age at diagnosis of UM among patients with ODM was 62 years. One patient had bilateral tumours. UM was diagnosed during a routine-examination in two cases. All tumours were medium (7/11) or large (4/11) in size, with a mean maximum base of 13 mm and height of 7 mm. No patient had extraocular extension or metastatic disease at diagnosis. Enucleation was done in five cases and I-125-brachytherapy in six. The mean follow-up was 43 months. One patient died because of metastasis 2 years after enucleation; one patient is currently on treatment of systemic metastasis 11 years after. CONCLUSIONS: ODM is more frequent in spanish population with UM than in American population. Despite the risk of UM in ODM, it is often diagnosed late when a conservative treatment is not indicated.
Keywords: Melanoma ocular
ISSN: 0950-222X
Peer Review: SI
DOI: 10.1038/eye.2011.257
Language: eng
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:DEP03 - Artículos de revista

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