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    Por favor, use este identificador para citar o enlazar este ítem:http://uvadoc.uva.es/handle/10324/38727

    Título
    Zinc nutritional status in patients with cystic fibrosis
    Autor
    Escobedo Monge, Marlene Fabiola
    Barrado Esteban, EnriqueAutoridad UVA Orcid
    Alonso Vicente, CarmenAutoridad UVA
    Redondo del Río, María PazAutoridad UVA
    Marugán de Miguelsanz, José ManuelAutoridad UVA
    Año del Documento
    2019
    Editorial
    MDPI
    Descripción
    Producción Científica
    Documento Fuente
    NUTRIENTS, 2019, 11, 150
    Résumé
    Background: Zinc is an essential nutrient for all forms of life and its deficiency affects the normal growth and development of human beings. Objective: The main aim was to investigate zinc nutritional status by serum zinc concentration (SZC) and dietary zinc intake and their association in cystic fibrosis (CF) patients. Methods: A cross-sectional study was conducted in CF patients. Anthropometric measurements and respiratory and pancreatic tests were conducted. Hypozincemia was determined by SZC while using atomic absorption spectrophotometry and dietary zinc deficiency by prospective 72-h dietary surveys. Results: Mean SZC (87.2 ± 16.7 μg/dL) and dietary zinc intake (97 ± 26.9% Dietary Reference Intake) were normal. Three of 17 patients with CF (17.6%) had hypozincemia and four (23.5%) had a dietary zinc deficiency. No patient with dietary zinc deficiency had hypozincemia. A positive and significant association was observed between SZC and Z-score of BMI-for-age (p = 0.048) and weight-for-height (p = 0.012) and between dietary zinc intake and energy intake (EI, p = 0.036) and Z-score of weight-for-high (p = 0.029). Conclusion: SZC was associated with the nutritional status, expressed as BMI (Body Mass Index) and weight-for-height Z score, and dietary zinc intake with EI and weight-for-height Z-score. No patient with hypozincemia had dietary zinc deficiency. This situation should alert us to a marginal zinc deficiency and it may explain why there were no overlapping cases between the two groups. We suggest that probably 41% of the cases in this study would be at elevated risk of zinc deficiency and a zinc supplementation may be considered.
    Palabras Clave
    serum zinc concentration; hypozincemia; dietary zinc intake; dietary zinc deficiency; cystic fibrosis; marginal zinc deficiency
    ISSN
    2072-6643
    Revisión por pares
    SI
    DOI
    10.3390/nu11010150
    Version del Editor
    https://www.mdpi.com/2072-6643/11
    Propietario de los Derechos
    MDPI
    Idioma
    eng
    URI
    http://uvadoc.uva.es/handle/10324/38727
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
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    • DEP60 - Artículos de revista [112]
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    nutrients-11-00150.pdf
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