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dc.contributor.authorJiménez López, María del Pilar 
dc.contributor.authorTejero del Río, Jesús
dc.contributor.authorCordoba Diaz, Damián
dc.contributor.authorQuinto Fernández, Emiliano José 
dc.contributor.authorGarrosa García, Manuel 
dc.contributor.authorGayoso Rodríguez, Manuel José 
dc.contributor.authorGirbés Juan, Tomás 
dc.date.accessioned2020-06-04T11:17:27Z
dc.date.available2020-06-04T11:17:27Z
dc.date.issued2015
dc.identifier.citationToxins, 2015, vol. 7, n. 3. p. 648-658es
dc.identifier.issn2072-6651es
dc.identifier.urihttp://uvadoc.uva.es/handle/10324/40990
dc.descriptionProducción Científicaes
dc.description.abstractSambucus ebulus L. (dwarf elder) is a medicinal plant, the usefulness of which also as food is restricted due to its toxicity. In the last few years, both the chemistry and pharmacology of Sambucus ebulus L. have been investigated. Among the structural and functional proteins present in the plant, sugar-binding proteins (lectins) with or without anti-ribosomal activity and single chain ribosome-inactivating proteins (RIPs) have been isolated. RIPs are enzymes (E.C. 3.2.2.22) that display N-glycosidase activity on the 28S rRNA subunit, leading to the inhibition of protein synthesis by arresting the step of polypeptide chain elongation. The biological role of all these proteins is as yet unknown. The evidence suggests that they could be involved in the defense of the plant against predators and viruses or/and a nitrogen store, with an impact on the nutritional characteristics and food safety. In this mini-review we describe all the isoforms of ebulin that have to date been isolated from dwarf elder, as well as their functional characteristics and potential uses, whilst highlighting concern regarding ebulin toxicity.es
dc.format.mimetypeapplication/pdfes
dc.language.isoenges
dc.publisherMDPIes
dc.rights.accessRightsinfo:eu-repo/semantics/openAccesses
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subject.classificationDwarf Elderes
dc.subject.classificationSaúco menores
dc.subject.classificationLectines
dc.subject.classificationLectinaes
dc.subject.classificationEbulines
dc.subject.classificationEbulinaes
dc.subject.classificationRicines
dc.subject.classificationRicinaes
dc.titleEbulin from dwarf elder (Sambucus ebulus L.): A mini-reviewes
dc.typeinfo:eu-repo/semantics/articlees
dc.rights.holder© 2015 MDPIes
dc.identifier.doi10.3390/toxins7030648es
dc.relation.publisherversionhttps://www.mdpi.com/2072-6651/7/3/648es
dc.peerreviewedSIes
dc.description.projectJunta de Castilla y León (Grupo de Excelencia GR106)es
dc.description.projectUniversidad Complutense de Madrid (research group 950247)es
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones


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