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    Por favor, use este identificador para citar o enlazar este ítem:http://uvadoc.uva.es/handle/10324/40990

    Título
    Ebulin from dwarf elder (Sambucus ebulus L.): A mini-review
    Autor
    Jiménez López, María del PilarAutoridad UVA Orcid
    Tejero Del Rio, JesúsAutoridad UVA
    Córdoba Diaz, Damián
    Quinto Fernández, Emiliano JoséAutoridad UVA Orcid
    Garrosa García, ManuelAutoridad UVA Orcid
    Gayoso Rodríguez, Manuel JoséAutoridad UVA Orcid
    Girbés Juan, TomásAutoridad UVA Orcid
    Año del Documento
    2015
    Editorial
    MDPI
    Descripción
    Producción Científica
    Documento Fuente
    Toxins, 2015, vol. 7, n. 3. p. 648-658
    Zusammenfassung
    Sambucus ebulus L. (dwarf elder) is a medicinal plant, the usefulness of which also as food is restricted due to its toxicity. In the last few years, both the chemistry and pharmacology of Sambucus ebulus L. have been investigated. Among the structural and functional proteins present in the plant, sugar-binding proteins (lectins) with or without anti-ribosomal activity and single chain ribosome-inactivating proteins (RIPs) have been isolated. RIPs are enzymes (E.C. 3.2.2.22) that display N-glycosidase activity on the 28S rRNA subunit, leading to the inhibition of protein synthesis by arresting the step of polypeptide chain elongation. The biological role of all these proteins is as yet unknown. The evidence suggests that they could be involved in the defense of the plant against predators and viruses or/and a nitrogen store, with an impact on the nutritional characteristics and food safety. In this mini-review we describe all the isoforms of ebulin that have to date been isolated from dwarf elder, as well as their functional characteristics and potential uses, whilst highlighting concern regarding ebulin toxicity.
    Palabras Clave
    Dwarf Elder
    Saúco menor
    Lectin
    Lectina
    Ebulin
    Ebulina
    Ricin
    Ricina
    ISSN
    2072-6651
    Revisión por pares
    SI
    DOI
    10.3390/toxins7030648
    Patrocinador
    Junta de Castilla y León (Grupo de Excelencia GR106)
    Universidad Complutense de Madrid (research group 950247)
    Version del Editor
    https://www.mdpi.com/2072-6651/7/3/648
    Propietario de los Derechos
    © 2015 MDPI
    Idioma
    eng
    URI
    http://uvadoc.uva.es/handle/10324/40990
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
    Aparece en las colecciones
    • BIOFORGE - Artículos de revista [89]
    Zur Langanzeige
    Dateien zu dieser Ressource
    Nombre:
    Ebulin-from-dwarf-elder.pdf
    Tamaño:
    500.9Kb
    Formato:
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