• español
  • English
  • français
  • Deutsch
  • português (Brasil)
  • italiano
    • español
    • English
    • français
    • Deutsch
    • português (Brasil)
    • italiano
    • español
    • English
    • français
    • Deutsch
    • português (Brasil)
    • italiano
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Ricerca

    Tutto UVaDOCArchiviData di pubblicazioneAutoriSoggettiTitoli

    My Account

    Login

    Estadísticas

    Ver Estadísticas de uso

    Compartir

    Mostra Item 
    •   UVaDOC Home
    • PRODUZIONE SCIENTIFICA
    • Departamentos
    • Dpto. Bioquímica y Biología Molecular y Fisiología
    • DEP06 - Artículos de revista
    • Mostra Item
    •   UVaDOC Home
    • PRODUZIONE SCIENTIFICA
    • Departamentos
    • Dpto. Bioquímica y Biología Molecular y Fisiología
    • DEP06 - Artículos de revista
    • Mostra Item
    • español
    • English
    • français
    • Deutsch
    • português (Brasil)
    • italiano

    Exportar

    RISMendeleyRefworksZotero
    • edm
    • marc
    • xoai
    • qdc
    • ore
    • ese
    • dim
    • uketd_dc
    • oai_dc
    • etdms
    • rdf
    • mods
    • mets
    • didl
    • premis

    Citas

    Por favor, use este identificador para citar o enlazar este ítem:http://uvadoc.uva.es/handle/10324/42705

    Título
    Supercritical rosemary extracts, their antioxidant activity and effect on hepatic tumor progression
    Autor
    Vicente, Gonzalo
    Molina, Susana
    González-Vallinas Garrachón, MargaritaAutoridad UVA
    García Risco, Mónica R.
    Fornari, Tiziana
    Reglero, Guillermo
    Ramírez de Molina, Ana
    Año del Documento
    2013
    Editorial
    Elsevier
    Descripción
    Producción Científica
    Documento Fuente
    The Journal of Supercritical Fluids, 2013, vol. 79, p. 101-108
    Abstract
    The use of supercritical fluid technology as an innovative technology to extract bioactive compounds has grown considerably in recent decades. Particularly, the recovery of antioxidants from different herbs is a matter of continuous research and development. Antioxidants can protect cells against the effects of free radicals and thus, play an important role in heart illness, cancer and other diseases. Rosemary (Rosmarinus officinalis L.) has been recognized as one of the Lamiaceae plant with many important biological activities. Particularly, large antioxidant power has been recognized in rosemary and main substances related with this activity were the phenolic diterpenes such as carnosol, rosmanol, carnosic acid, methyl carnosate, and phenolic acids such as the rosmarinic and caffeic acids. Moreover, carnosic acid and carnosol are recognized as the most abundant antioxidants present in rosemary. In this work, supercritical fluid technology was applied to produce rosemary extracts with different compositions and thus, with different bioactivity properties. Selected extracts, from the variety of samples obtained, were used to study the capability of rosemary supercritical extracts to inhibit the proliferation of human liver carcinoma cells. These extracts showed a dose-dependent effect on inhibiting the proliferation of human hepatoma cells. Moreover, observed citostaticity appeared to be significantly influenced by their different composition, suggesting a relevant role of the technology to produce the extracts and the consequently obtained compositions on the potential antitumoral activity of rosemary.
    Materias Unesco
    3207.13 Oncología
    Palabras Clave
    Cáncer de hígado
    Romero
    ISSN
    0896-8446
    Revisión por pares
    SI
    DOI
    10.1016/j.supflu.2012.07.006
    Version del Editor
    https://www.sciencedirect.com/science/article/abs/pii/S0896844612002458?via%3Dihub
    Propietario de los Derechos
    © Elsevier
    Idioma
    eng
    URI
    http://uvadoc.uva.es/handle/10324/42705
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
    Aparece en las colecciones
    • DEP06 - Artículos de revista [353]
    Mostra tutti i dati dell'item
    Files in questo item
    Nombre:
    Supercritical-rosemary-extracts.pdf
    Tamaño:
    450.2Kb
    Formato:
    Adobe PDF
    Thumbnail
    Mostra/Apri
    Attribution-NonCommercial-NoDerivatives 4.0 InternacionalLa licencia del ítem se describe como Attribution-NonCommercial-NoDerivatives 4.0 Internacional

    Universidad de Valladolid

    Powered by MIT's. DSpace software, Version 5.10