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Título
Non-steroidal anti-inflammatory drugs (NSAIDs) and neuroprotection in the elderly: a view from the mitochondria
Año del Documento
2015
Editorial
Medknow Publications
Descripción
Producción Científica
Documento Fuente
Neural Regeneration Research, 2015, vol. 10, n. 9. p. 1371-1372
Abstract
The most important risk factor for stroke and neurodegeneration is
aging. In fact, survival after stroke diminishes largely with aging. In
fact, recovery after brain artery occlusion is dramatically worsened
by aging, even normal aging is associated with neuron damage and
cognitive decline. Mechanisms involved in aging-related, cognitive
decline and susceptibility to neuron damage in stroke and neurodegeneration are largely unknown. One of the most important mechanisms contributing to neural dysfunction and death is excitotoxicity. This process is based on the fact that the excessive glutamate
receptor stimulation may lead to neuronal damage. This overstimulation may be due to increased concentration of glutamate, or the
prolonged activation of receptors.
Palabras Clave
Aging
Envejecimiento
Neuroprotection
Neuroprotección
Mitochondria
Mitocondrias
ISSN
1876-7958
Revisión por pares
SI
Patrocinador
Junta de Castilla y León (grants VA145U13, BIO/VA33/13 and BIO103/VA45/11)
Ministerio de Economía, Industria y Competitividad (grant BFU2012- 37146)
Ministerio de Economía, Industria y Competitividad (grant BFU2012- 37146)
Version del Editor
Propietario de los Derechos
© 2015 Medknow Publications
Idioma
eng
Tipo de versión
info:eu-repo/semantics/publishedVersion
Derechos
openAccess
Collections
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