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    Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/53963

    Título
    Recombinant proteins-based strategies in bone tissue engineering
    Autor
    Ribeiro Paulini, Marina
    Camal Ruggieri, Iván Nadir
    Ramallo, Melina
    Alonso Rodrigo, MatildeAutoridad UVA Orcid
    Rodríguez Cabello, José CarlosAutoridad UVA Orcid
    Esbrit, Pedro
    Mardegan Issa, João Paulo
    Feldman, Sara
    Año del Documento
    2021
    Editorial
    MDPI
    Descripción
    Producción Científica
    Documento Fuente
    Biomolecules, 2021, vol. 12, n. 1, p. 3
    Abstract
    The increase in fracture rates and/or problems associated with missing bones due to accidents or various pathologies generates socio-health problems with a very high impact. Tissue engineering aims to offer some kind of strategy to promote the repair of damaged tissue or its restoration as close as possible to the original tissue. Among the alternatives proposed by this specialty, the development of scaffolds obtained from recombinant proteins is of special importance. Furthermore, science and technology have advanced to obtain recombinant chimera’s proteins. This review aims to offer a synthetic description of the latest and most outstanding advances made with these types of scaffolds, particularly emphasizing the main recombinant proteins that can be used to construct scaffolds in their own right, i.e., not only to impregnate them, but also to make scaffolds from their complex structure, with the purpose of being considered in bone regenerative medicine in the near future.
    Materias Unesco
    32 Ciencias Médicas
    24 Ciencias de la Vida
    23 Química
    Palabras Clave
    Recombinant proteins
    Bone
    Tissue engineering
    BMP-2
    Scaffold
    ISSN
    2218-273X
    Revisión por pares
    SI
    DOI
    10.3390/biom12010003
    Patrocinador
    Gobierno Español, (Grant/Award Numbers: MAT2016-78903-R, RTI2018-096320-B-C22, PID2019-110709RB-I00, and RED2018-102417-T)
    Junta de Castilla y León, (Grant/Award Numbers:VA317P18, Infrared2018-UVA06)
    Interreg V España-Portugal POCTEP, (Grant/AwardNumber: 0624_2IQBIONEURO_6_E)
    Version del Editor
    https://www.mdpi.com/2218-273X/12/1/3
    Propietario de los Derechos
    © 2021 The Author(s)
    Idioma
    eng
    URI
    https://uvadoc.uva.es/handle/10324/53963
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
    Aparece en las colecciones
    • BIOFORGE - Artículos de revista [89]
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    Universidad de Valladolid

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