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    Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/61916

    Título
    Cerebral white matter connectivity in adolescent idiopathic scoliosis: A diffusion magnetic resonance imaging study
    Autor
    Noriega González, David CésarAutoridad UVA
    Crespo Sanjuan, Jesús
    Ardura Aragón, FrancíscoAutoridad UVA Orcid
    Calabia del Campo, Juan
    Alberola López, CarlosAutoridad UVA Orcid
    Luis García, Rodrigo deAutoridad UVA Orcid
    Caballero García, AlbertoAutoridad UVA
    Córdova Martínez, AlfredoAutoridad UVA Orcid
    Año del Documento
    2022
    Editorial
    MDPI
    Descripción
    Producción Científica
    Documento Fuente
    Children, 2022, Vol. 9, Nº. 7, 1023
    Resumo
    Adolescent idiopathic scoliosis (AIS) is characterized by the radiographic presence of a frontal plane curve, with a magnitude greater than 10° (Cobb technique). Diffusion MRI can be employed to assess the cerebral white matter. The aim of this study was to analyze, by means of MRI, the presence of any alteration in the connectivity of cerebral white matter in AIS patients. In this study, 22 patients with AIS participated. The imaging protocol consisted in T1 and diffusion-weighted acquisitions. Based on the information from one of the diffusion acquisitions, a whole brain tractography was performed with the MRtrix tool. Tractography is a method to deduce the trajectory of fiber bundles through the white matter based on the diffusion MRI data. By combining cortical segmentation with tractography, a connectivity matrix of size 84 × 84 was constructed using FA (fractional anisotropy), and the number of streamlines as connectomics metrics. The results obtained support the hypothesis that alterations in cerebral white matter connectivity in patients with adolescent idiopathic scoliosis (AIS) exist. We consider that the application of diffusion MRI, together with transcranial magnetic stimulation neurophysiologically, is useful to search the etiology of AIS.
    Materias (normalizadas)
    Adolescent idiopathic scoliosis
    Scoliosis
    Escoliosis
    Adolescentes - Enfermedades
    Spine - Diseases - Treatment
    Columna vertebral - Anomalías - Tratamiento
    Magnetic resonance imaging
    Resonancia magnética
    Fractional anisotropy
    Connectomics
    Artificial intelligence
    Neurosciences
    Tractography
    Neurology
    Materias Unesco
    32 Ciencias Médicas
    1203.04 Inteligencia Artificial
    2490 Neurociencias
    3205.07 Neurología
    ISSN
    2227-9067
    Revisión por pares
    SI
    DOI
    10.3390/children9071023
    Version del Editor
    https://www.mdpi.com/2227-9067/9/7/1023
    Propietario de los Derechos
    © 2022 The Authors
    Idioma
    eng
    URI
    https://uvadoc.uva.es/handle/10324/61916
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
    Aparece en las colecciones
    • DEP11 - Artículos de revista [242]
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    Cerebral-White-Matter-Connectivity-in-Adolescent-Idiopathic-Scoliosis.pdf
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    Universidad de Valladolid

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