Mostrar el registro sencillo del ítem
dc.contributor.author | Antonio de Luis, Daniel | |
dc.contributor.author | Izaola, Olatz | |
dc.contributor.author | Primo, David | |
dc.contributor.author | Aller de la Fuente, Rocío | |
dc.date.accessioned | 2024-01-16T09:44:55Z | |
dc.date.available | 2024-01-16T09:44:55Z | |
dc.date.issued | 2018 | |
dc.identifier.citation | Clin Nutr. 2018 Dec;37(6 Pt A):2280-2283 | es |
dc.identifier.issn | 0261-5614 | es |
dc.identifier.uri | https://uvadoc.uva.es/handle/10324/64580 | |
dc.description.abstract | Background & aims: Omentin-1 might play a role on insulin resistance, dyslipidemia and obesity. The aim of this investigation was to evaluate the influence of weight loss on omentin-1 concentrations after a hypocaloric diet with Mediterranean pattern. Methods: A Caucasian sample of 67 obese patients was analyzed before and after 3 months on a hypocaloric diet. Anthropometric parameters, blood pressure, fasting blood glucose, C-reactive protein (CRP), fasting insulin, insulin resistance (HOMA-IR), lipid concentrations and omentin-1 were measured. Results: Sixty-seven obese subjects were enrolled in the study. The mean age was 48.3 ± 8.0 years (range: 25e66) and the mean BMI 34.5 ± 4.8 kg/m2 (range: 30.2e40.8). Gender distribution was 50 females (74.6%) and 17 males (25.4%). After dietary intervention and in males and females; body mass index, weight, fat mass, waist circumference, blood pressure, glucose, LDL cholesterol, insulin and HOMA-IR decreased. Omentin-1 levels increase after dietary intervention (males vs females) (delta basal vs 3 months: 10.0 ± 3.8 ng/dl: p ¼ 0.01 vs 9.9 ± 4.1 ng/dl; p ¼ 0.03). In the multiple regression analysis adjusted for age and sex; BMI and insulin remained independently associated with baseline and posttreatment levels of omentin-1. Conclusions: Our investigation showed a significant increase in omentin-1 levels after weight loss secondary to a hypocaloric diet with a Mediterranean pattern. | es |
dc.format.mimetype | application/pdf | es |
dc.language.iso | eng | es |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
dc.title | Modifications of serum levels of omentin-1 and other cardiovascular risk factors following weight loss secondary to a Mediterranean hypocaloric diet | es |
dc.type | info:eu-repo/semantics/article | es |
dc.identifier.doi | 10.1016/j.clnu.2017.11.009 | es |
dc.identifier.publicationfirstpage | 2280 | es |
dc.identifier.publicationissue | 6 | es |
dc.identifier.publicationlastpage | 2283 | es |
dc.identifier.publicationtitle | Clinical Nutrition | es |
dc.identifier.publicationvolume | 37 | es |
dc.peerreviewed | SI | es |
dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | es |