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    Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/73258

    Título
    Phosphate chelation over calcium impacts yeast growth and lipid production from short-chain fatty acids-rich media
    Autor
    Morales Palomo, Sergio
    Tomás Pejó, Elia
    González Fernández, María Cristina
    Año del Documento
    2024
    Editorial
    Elsevier
    Descripción
    Producción Científica
    Documento Fuente
    Environmental Technology & Innovation, noviembre 2024, vol. 36, 103767
    Abstract
    Some oleaginous yeasts have the ability to produce microbial oils from alternative carbon sources, such as short-chain fatty acids (SCFAs). Nevertheless, there is still a lack of information about the possible effects that media nutrients have on yeast metabolisms when using SCFAs. For instance, inorganic phosphate (PO43-) has been reported to promote yeast growth in literature but its chelating effect over other elements such as calcium (Ca2+) is often not considered in fermentation processes while limitation of nitrogen is probably the most studied. Attending at the need to better understand the role of PO43-, this work assessed the lipid production capacity of Yarrowia lipolytica ACA DC 50109, both in synthetic and real SCFAs-rich media, at different SCFAs concentrations and PO43-:Ca2+ ratios. Reducing PO43-:Ca2+ ratio was identified to be an important factor to improve yeast growth, reaching the highest lipid content (52.7 ± 0.9 % w/w) and lipid yield (0.31 ± 0.01 w/w) in media without PO43-. These results demonstrated the importance of Ca2+ availability in the medium and nutrients interactions in yeast growth that are often underestimated.
    Palabras Clave
    Phosphate
    Calcium
    Chelation
    Lipids
    Yarrowia lipolytica
    Short-chain fatty acids
    ISSN
    2352-1864
    Revisión por pares
    SI
    DOI
    10.1016/j.eti.2024.103767
    Patrocinador
    Ministerio de Ciencia e Innovación (PID2020-119403RBC21, PCI2021-121936, PRE2018-086477, RYC2019-027773-I)
    Version del Editor
    https://www.sciencedirect.com/science/article/pii/S2352186424002438
    Propietario de los Derechos
    © 2024 The Authors
    Idioma
    eng
    URI
    https://uvadoc.uva.es/handle/10324/73258
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
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    • DEP48 - Artículos de revista [265]
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