| dc.contributor.author | Prieto, Elena | |
| dc.contributor.author | Andrés Juan, Celia | |
| dc.contributor.author | Nieto Román, Francisco Javier | |
| dc.date.accessioned | 2025-11-27T11:31:56Z | |
| dc.date.available | 2025-11-27T11:31:56Z | |
| dc.date.issued | 2025 | |
| dc.identifier.citation | Organic & Biomolecular Chemistry, 2025, vol. 23, p 10596-10605. | es |
| dc.identifier.issn | 1477-0520 | es |
| dc.identifier.uri | https://uvadoc.uva.es/handle/10324/80120 | |
| dc.description | Producción Científica | |
| dc.description.abstract | The α-hydroxyamide moiety is an important structural component in a wide variety of biologically active
compounds and natural products. Herein, we describe a highly efficient and practical approach towards
chiral quaternary α-alkynyl-α-hydroxyamides by Me2Zn-mediated addition of terminal alkynes to α-keto
amides. The desired products are obtained in good yields and enantioselectivities with broad substrate
and reagent scopes. | es |
| dc.format.mimetype | application/pdf | es |
| dc.language.iso | spa | es |
| dc.publisher | The Royal Society of Chemistry | es |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | es |
| dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | Química Orgánica Sintética | |
| dc.subject | Catálisis Asimétrica | |
| dc.subject | Química Organometálica | |
| dc.title | Synthesis of chiral α-alkynyl-α-hydroxyamides by enantioselective alkynylation of α-keto amides | es |
| dc.type | info:eu-repo/semantics/article | es |
| dc.rights.holder | © The Royal Society of Chemistry 2025 | |
| dc.identifier.doi | 10.1039/d5ob01546d | es |
| dc.relation.publisherversion | https://pubs.rsc.org/en/content/articlelanding/2025/ob/d5ob01546d | |
| dc.identifier.publicationfirstpage | 10596 | es |
| dc.identifier.publicationissue | 46 | es |
| dc.identifier.publicationlastpage | 10605 | es |
| dc.identifier.publicationtitle | Organic & Biomolecular Chemistry | es |
| dc.identifier.publicationvolume | 23 | es |
| dc.peerreviewed | SI | es |
| dc.description.project | Junta de Castilla y León (projects FEDER-VA115P17 and VA149G18) | es |
| dc.identifier.essn | 1477-0539 | es |
| dc.rights | Atribución 4.0 Internacional | |
| dc.type.hasVersion | info:eu-repo/semantics/publishedVersion | es |
| dc.subject.unesco | 2306 Química Orgánica | |
| dc.subject.unesco | 2301 Química Analítica | |
Except where otherwise noted, this item's license is described as Atribución 4.0 Internacional