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Title: Clinical and Molecular Inflammatory Response in Sjögren Syndrome–Associated Dry Eye Patients Under Desiccating Stress
Authors: López Miguel, Alberto
Tesón, Marisa
Martín Montañez, Vicente
Enríquez de Salamanca, Amalia
Sternd, Michael E.
Calonge Cano, Margarita
González García, María J.
Issue Date: 2016
Publisher: Elsevier Masson
Description: Producción Científica
Citation: American Journal of Ophthalmology, 2016, Vol.161, p.133–141 e2
Abstract: To evaluate the response of the lacrimal function unit in Sjogren syndrome (SS)-associated dry eye patients exposed to 2 simulated daily life environ-mental conditions. Fourteen female SS dry eye patients were exposed for 2 hours to a controlled normal condition (23 C, 45% relative humidity, and air flow 0.10 m/s) and a controlled adverse condition that simulates desic- cating stress (23 C, 5% relative humidity, and air flow 0.10 m/s). The following dry eye tests were performed before and after the exposure: tear osmolarity, phenol red thread test, conjunctival hyperemia, fluorescein tear break-up time, corneal fluorescein staining, conjunctival lissamine green staining, and Schirmer test. Levels of 16 molecules were analyzed in tears by multiplex immu- nobead analysis.
Keywords: Ojo seco
Sjogren, Síndrome de
Peer Review: SI
Sponsor: Junta de Castilla y León (programa de apoyo a proyectos de investigación – Ref. VA174U14)
Publisher Version:
Language: eng
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:DEP11 - Artículos de revista

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