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Por favor, use este identificador para citar o enlazar este ítem: http://uvadoc.uva.es/handle/10324/21744
Título: Analysis of the Non-stationarity of Neural Activity during an Auditory Oddball Task in Schizophrenia
Autor: Nuñez Novo, Pablo
Poza Crespo, Jesús
Gómez Pilar, Javier
Bachiller, Alejandro
Gómez Peña, Carlos
Lubeiro, Alba
Molina, Vicente
Hornero Sánchez, Roberto
Año del Documento: 2016
Editorial: IEEE Conference Publications
Descripción: Producción Científica
Documento Fuente: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference, 2016, p. 3724 - 3727
Resumen: The aim of this study was to characterize brain dynamics during an auditory oddball task. For this purpose, a measure of the non-stationarity of a given time-frequency representation (TFR) was applied to electroencephalographic (EEG) signals. EEG activity was acquired from 20 schizophrenic (SCH) patients and 20 healthy controls while they underwent a three-stimulus auditory oddball task. The Degree of Stationarity (DS), a measure of the non-stationarity of the TFR, was computed using the continuous wavelet transform. DS was calculated for both the baseline [-300 0] ms and active task [150 550] ms windows of a P300 auditory oddball task. Results showed a statistically significant increase (p<0.05) in non-stationarity for controls during the cognitive task in the central region, while less widespread statistically significant differences were obtained for SCH patients, especially in the beta-2 and gamma bands. Our findings support the relevance of DS as a means to study cerebral processing in SCH. Furthermore, the lack of statistically significant changes in DS for SCH patients suggests an abnormal reorganization of neural dynamics during an oddball task.
Materias (normalizadas): Schizophrenia
ISSN: 1557-170X
Revisión por Pares: SI
DOI: 10.1109/EMBC.2016.7591537
Patrocinador: Ministerio de Economía y Competitividad (TEC2014-53196-R)
Junta de Castilla y León (VA059U13)
Version del Editor: http://ieeexplore.ieee.org/servlet/opac?punumber=1000269
Idioma: eng
URI: http://uvadoc.uva.es/handle/10324/21744
Derechos: info:eu-repo/semantics/openAccess
Aparece en las colecciones:DEP71 - Artículos de revista

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