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Title: Circular Order Aggregation and its Application to Cell-cycle Genes Expressions
Authors: Barragán, Sandra
Rueda, Cristina
Fernández, Miguel
Issue Date: 2017
Publisher: IEEE
Citation: IEEE/ACM Transactions on Computational Biology and Bioinformatics.
Abstract: The aim of circular order aggregation is to find a circular order on a set of n items using angular values from p heterogeneous data sets. This problem is new in the literature and has been motivated by the biological question of finding the order among the peak expression of a group of cell cycle genes. In this paper, two very different approaches to solve the problem that use pairwise and triplewise information are proposed. Both approaches are analyzed and compared using theoretical developments and numerical studies, and applied to the cell cycle data that motivated the problem.
Peer Review: SI
DOI: 10.1109/TCBB.2016.2565469
Sponsor: Ministerio de Ciencia e Innovación grant (MTM2012-37129)
Ministerio de Ciencia e Innovación grant MTM2015-71217-R
European Social Fund within the Programa Operativo Castilla y León 2007–2013
Publisher Version:
Rights Owner: IEEE
Language: eng
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:DEP24 - Artículos de revista

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