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Title: Is it true coeliacs do not digest gliadin ?. Degradation pattern of gliadin in coeliac disease small intestinal mucosa
Authors: Bernardo, D.
Garrote Adrados, José Antonio
Nadal, I.
León, Alberto José
Calvo Romero, María del Carmen
Fernández Salazar, Luis Ignacio
Blanco Quirós, Alfredo
Sanz, Y.
Arranz, E.
Issue Date: 2009
Publisher: Instituto de Biología y Genética Molecular
Citation: Gut, 2009, vol. 000 No 000
Abstract: Prolyl-endopeptidase supplementation has been proposed to favour gliadin degradation as an alternative treatment for coeliac disease (CD), although the real usefulness of this therapy in vivo is still under discussion. 1 However, our data point to alternative treatments aiming to modify the intestinal microbiota in patients with CD by the use of probiotics and/or prebiotics. We propose that the induction of gliadin proteolysis in the human gut might not be the solution but the origin of CD.
Keywords: Enfermedad celíaca
Intestinos - Enfermedades
Peer Review: SI
Language: eng
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:DEP55 - Artículos de revista

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