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Title: Embryonic cerebrospinal fluid in brain development: neural progenitor control
Authors: Gato Casado, Ángel Luis
Alonso Revuelta, María Isabel
Martín, Cristina
Carnicero Gila, Estela María
Moro Balbás, José Antonio
Fernández Gómez, José María Fidel
Lamus Molina, José Francisco
Desmond, Mary E.
Issue Date: 2014
Publisher: Karger
Description: Producción Científica
Citation: Croat Medical J. Agosto 2014, 55(4) 299-305
Abstract: Due to the effort of several research teams across the world, today we have a solid base of knowledge on the liquid contained in the brain cavities, its composition, and biological roles. Although the cerebrospinal fluid (CSF) is among the most relevant parts of the central nervous system from the physiological point of view, it seems that it is not a permanent and stable entity because its composition and biological properties evolve across life. So, we can talk about different CSFs during the vertebrate life span. In this review, we focus on the CSF in an interesting period, early in vertebrate development before the formation of the choroid plexus. This specific entity is called “embryonic CSF.” Based on the structure of the compartment, CSF composition, origin and circulation, and its interaction with neuroepithelial precursor cells (the target cells) we can conclude that embryonic CSF is different from the CSF in later developmental stages and from the adult CSF. This article presents arguments that support the singularity of the embryonic CSF, mainly focusing on its influence on neural precursor behavior during development and in adult life.
Keywords: Nervioso central, Sistema
ISSN: 0353-9504
Peer Review: SI
DOI: 10.3325/cmj.2014.55.299
Language: eng
Rights: info:eu-repo/semantics/openAccess
Appears in Collections:DEP05 - Artículos de revista

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