Por favor, use este identificador para citar o enlazar este ítem:http://uvadoc.uva.es/handle/10324/13529
Título
A new method for detection of cyclic circadian genes using order restricted inference
Director o Tutor
Año del Documento
2015
Titulación
Máster en Investigación en Matemáticas
Abstract
Identification of periodic patterns in gene expression data is important for studying
the regulation mechanism of the circadian system. The information available is
often given only by one or two cycles. Consequently, the number of observations is
not enough to fit certain models, such as Fourier's models, properly. Some authors
have already developed procedures or algorithms among which the JTK CYCLE
algorithm is the most popular one.
We propose a new method to identify cyclic gene expressions based on euclidean
and circular order restricted inference. Validation of the method is made through
real data sets and simulations. Moreover, we compare the results obtained by the
method with other detecting methods developed in the literature.
Materias (normalizadas)
Algoritmo JTK Cycle
Ciclo circadiano - Expresión génica
Departamento
Departamento de Estadística e Investigación Operativa
Idioma
eng
Derechos
openAccess
Collections
- Trabajos Fin de Máster UVa [6381]
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