Por favor, use este identificador para citar o enlazar este ítem:http://uvadoc.uva.es/handle/10324/5882
Título
Relation of resistin levels with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetes obese patients
Autor
Año del Documento
2010
Editorial
Elsevier
Descripción
Producción Científica
Documento Fuente
Diabetes Research and Clinical Practice, 2010, vol. 89, p. 110-114
Résumé
Background: The aim of the present study was to explore the relationship of resistin levels
with cardiovascular risk factors, insulin resistance and inflammation in naı¨ve diabetic
patients.
Subjects: A population of 66 naı¨ve diabetic patients with obesity was analyzed. A complete
nutritional and biochemical evaluation was performed.
Results: The mean age 56.9 11.6 years and the mean BMI was 37.8 6.3. Patients were
divided in two groups by median resistin value (3.3 ng/ml), group I (patients with the low
values, average value 2.5 0.5) and group II (patients with the high values, average value
4.8 1.8). Patients in the group I had lower waist circumference, total cholesterol, LDLcholesterol
and C-reactive protein than patients in group II. Correlation analysis showed a
significant correlation among resistin levels and the independent variables; BMI (r = 0.26;
p < 0.05), waist circumference (r = 0.38; p < 0.05), fat mass (r = 0.28; p < 0.05), LDL-cholesterol
(r = 0.3; p < 0.05), C-reactive protein (r = 0.28; p < 0.05). In the multivariate analysis, resistin
concentration increase 0.024 ng/ml (CI 95%: 0.006–0.42) for each mg/dl of C-reactive protein.
Conclusion: Circulating resistins are associated with C-reactive protein in an independent
way in naı¨ve diabetic patients.
Materias (normalizadas)
Cardiovascular, Aparato - Enfermedades
Diabetes
ISSN
0168-8227
Revisión por pares
SI
Idioma
eng
Derechos
openAccess
Aparece en las colecciones
Fichier(s) constituant ce document
Excepté là où spécifié autrement, la license de ce document est décrite en tant que Attribution-NonCommercial-NoDerivatives 4.0 International