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    Por favor, use este identificador para citar o enlazar este ítem:https://uvadoc.uva.es/handle/10324/59450

    Título
    Relationship between the main components of the crystalline lens and the anterior chamber depth after cataract formation
    Autor
    Díez Montero, Cecilia
    López De La Rosa, AlbertoAutoridad UVA Orcid
    López Miguel, AlbertoAutoridad UVA Orcid
    Maldonado López, Miguel JoséAutoridad UVA Orcid
    Año del Documento
    2023
    Editorial
    Springer
    Descripción
    Producción Científica
    Documento Fuente
    Graefe's Archive for Clinical and Experimental Ophthalmology, 2023, 261, p. 2853-2861
    Résumé
    Purpose To assess the relationship between anterior chamber depth (ACD) and lens thickness (LT), as well as its three main components (anterior and posterior cortex and nucleus thickness), in cataractous and non-cataractous eyes, depending on the axial length (AxL). Methods Anterior and posterior cortex and nucleus thickness of the crystalline lens, ACD, and AxL were measured using optical low-coherence reflectometry in cataractous and non-cataractous eyes. They were also classified into hyperopia, emme- tropia, myopia, and high myopia, depending on AxL; thus, eight subgroups were created. A minimum sample size of 44 eyes (of 44 patients) for each group was recruited. Linear models were fitted for the whole sample and each AxL subgroup to assess if there were differences in the relationships between the crystalline lens variables and ACD, including age as a covariate. Results Three hundred seventy cataract patients (237 females, 133 males) and 250 non-cataract controls (180 females, 70 males), aged 70.5 ± 9.4 and 41.9 ± 15.5 years, respectively, were recruited. The mean AxL, ACD, and LT for the cataractous and non-cataractous eyes were 23.90 ± 2.05, 24.11 ± 2.11, 2.64 ± 0.45, and 2.91 ± 0.49, 4.51 ± 0.38, 3.93 ± 0.44 mm, respec- tively. The inverse relationship of LT, anterior and posterior cortex, and nucleus thickness with ACD was not significantly (p ≥ 0.26) different between cataractous and non-cataractous eyes. Further subclassification of the sample depending on AxL showed that the inverse relationship between the posterior cortex and ACD was no longer significant (p > 0.05) for any non-cataractous AxL group. LT, anterior and posterior cortex, and nucleus thickness was not significantly (p ≥ 0.43) different between cataractous and non-cataractous eyes for the whole sample, and all AxL groups after adjusting for age. Conclusions The presence of cataracts does not modify the inverse relationship of the LT, anterior and posterior cortex, and nucleus with ACD. And this relationship does not seem to depend importantly on AxL. Besides, the possible differences in LT, anterior and posterior cortex, and nucleus between cataractous and non-cataractous eyes may not be caused by lens opacification, but possibly by the progressive lens growth due to aging.
    Materias Unesco
    32 Ciencias Médicas
    3201.09 Oftalmología
    Palabras Clave
    Lens thickness
    Anterior cortex
    Posterior cortex
    Nucleus thickness
    Axial length
    Anterior chamber depth
    Cataract
    ISSN
    0721-832X
    Revisión por pares
    SI
    DOI
    10.1007/s00417-023-06080-7
    Patrocinador
    Ministerio de Economía y Competitividad (Instituto de Salud Carlos III) through Research Projects (RETICS RD16/008/0001)
    Publicación en abierto financiada por el Consorcio de Bibliotecas Universitarias de Castilla y León (BUCLE), con cargo al Programa Operativo 2014ES16RFOP009 FEDER 2014-2020 DE CASTILLA Y LEÓN, Actuación:20007-CL - Apoyo Consorcio BUCLE
    Version del Editor
    https://link.springer.com/article/10.1007/s00417-023-06080-7
    Propietario de los Derechos
    © 2023 The Author(s)
    Idioma
    eng
    URI
    https://uvadoc.uva.es/handle/10324/59450
    Tipo de versión
    info:eu-repo/semantics/publishedVersion
    Derechos
    openAccess
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    • DEP11 - Artículos de revista [242]
    • IOBA - Artículos de revista [80]
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